HitPredict

Interactor 1: RS27A (P15357)
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RpS27A

Interactor 2: Q9VZU7 (Q9VZU7)
Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12)
Gene: Usp5

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24292889
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UBA~ubiquitin, UCH~ubiquitin, ubiquitin~zf-UBP
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 156 Dm			1 827
+	Hs
		853454 RS27A_HUMAN (1-156): 1.18e-74: 221: 91.03		UBP5_HUMAN (2-825): 0: 690: 48.50
+	Hs
		853455 RL40_HUMAN (1-125): 2.43e-45: 146: 65.60		UBP5_HUMAN (2-825): 0: 690: 48.50
+	Rn
		93126 UBC_RAT (1-98): 1.15e-32: 123: 78.57		D3ZVQ0_RAT (2-825): 0: 695: 48.85
+	Rn
		92895 UBC_RAT (1-98): 1.15e-32: 123: 78.57		D3ZDI9_RAT (2-825): 0: 636: 42.52
+	At
		1167722 UBQ3_ARATH (1-77): 8.36e-36: 127: 94.81		UBP14_ARATH (1-825): 0: 599: 43.37
+	Sc
		509891 RL40A_YEAST (1-125): 4.27e-43: 140: 64.80		UBP14_YEAST (6-825): 2.81e-136: 425: 24.94
+	Sc
		509516 UBI4P_YEAST (1-76): 1.75e-34: 125: 96.05		UBP14_YEAST (6-825): 2.81e-136: 425: 24.94
+	Sc
		436462 RS31_YEAST (1-151): 7.2e-60: 184: 81.46		UBP8_YEAST (163-671): 9.34e-93: 301: 13.15
+	Hs
		987252 RS27A_HUMAN (1-156): 1.18e-74: 221: 91.03		UBP36_HUMAN (251-780): 6.08e-72: 258: 11.73
+	Hs
		987118 RS27A_HUMAN (1-156): 1.18e-74: 221: 91.03		UBP38_HUMAN (289-827): 9.13e-67: 242: 15.96
+	Sc
		509637 UBI4P_YEAST (1-76): 1.75e-34: 125: 96.05		UBP8_YEAST (163-671): 9.34e-93: 301: 13.15
+	At
		1192395 RL40B_ARATH (1-125): 1.72e-44: 144: 63.20		UBP15_ARATH (332-788): 8.12e-78: 272: 12.34
+	Hs
		967139 RL40_HUMAN (1-125): 2.43e-45: 146: 65.60		UBP46_HUMAN (307-672): 1.76e-79: 262: 17.52
+	Rn
		98870 RL40_RAT (1-125): 2.43e-45: 146: 65.60		UBP46_RAT (307-672): 2.93e-79: 261: 17.52
+	At
		1168007 UBQ3_ARATH (1-77): 8.36e-36: 127: 94.81		UBP15_ARATH (332-788): 8.12e-78: 272: 12.34
+	At
		1300626 UBQ10_ARATH (1-76): 1.79e-34: 126: 96.05		UBP15_ARATH (332-788): 8.12e-78: 272: 12.34
+	Sc
		509565 UBI4P_YEAST (1-76): 1.75e-34: 125: 96.05		UBP5_YEAST (331-657): 2.54e-73: 257: 16.23
+	Mm
		508936 UBB_MOUSE (1-76): 3.56e-34: 123: 100.00		UBP48_MOUSE (331-776): 3.21e-72: 258: 15.64
+	Rn
		93326 UBC_RAT (1-98): 1.15e-32: 123: 78.57		D4ACD3_RAT (332-823): 1.82e-65: 239: 15.60
+	Hs
		987504 RL40_HUMAN (1-125): 2.43e-45: 146: 65.60		UBP20_HUMAN (176-449): 5.43e-26: 116: 21.58