HitPredict

Interactor 1: NCBP2 (P52298)
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (Cell proliferation-inducing gene 55 protein) (NCBP 20 kDa subunit) (CBP20) (NCBP-interacting protein 1) (NIP1)
Gene: NCBP2

Interactor 2: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	32960270
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	NOPS~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008380 - RNA splicing
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 156 Hs			1 471
+	Mm
		1207997 CSTFT_MOUSE (31-148): 4.24e-35: 129: 24.37		NONO_MOUSE (1-471): 4.7e-94: 294: 98.31
+	Hs
		853881 NCBP2_HUMAN (1-156): 2.27e-48: 154: 100.00		PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42
+	Hs
		516425 NCBP2_HUMAN (1-156): 2.27e-48: 154: 100.00		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Ce
		71809 O45577_CAEEL (27-148): 4.43e-36: 128: 28.23		B3GWA1_CAEEL (67-335): 1.39e-73: 243: 44.98
+	Hs
		516495 PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41		PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42
+	Hs
		613388 NCBP2_HUMAN (1-156): 2.27e-48: 154: 100.00		SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92
+	Hs
		516608 PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41		PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41
+	Hs
		516339 PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		516689 PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41		PABP3_HUMAN (66-459): 5.94e-61: 211: 13.88
+	Hs
		703388 CSTF2_HUMAN (31-148): 1.11e-34: 128: 23.53		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Sc
		376958 NCBP2_YEAST (10-150): 3.97e-39: 132: 52.48		PABP_YEAST (30-384): 3.77e-37: 145: 16.50
+	Hs
		1031344 PABP4_HUMAN (4-156): 2.89e-27: 107: 17.18		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Hs
		516635 PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41		PABP5_HUMAN (78-205): 4.72e-26: 111: 26.76
+	Hs
		853975 NCBP2_HUMAN (1-156): 2.27e-48: 154: 100.00		RBM4_HUMAN (75-182): 7.64e-09: 59.3: 35.71
+	Hs
		474021 PABP4_HUMAN (4-156): 2.89e-27: 107: 17.18		PAB4L_HUMAN (139-369): 5.62e-18: 87.3: 14.09
+	Mm
		1207996 CSTFT_MOUSE (31-148): 4.24e-35: 129: 24.37		RBM4_MOUSE (75-182): 5.42e-09: 59.7: 35.71
+	Hs
		516484 PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41		ELAV2_HUMAN (150-210): 9.69e-14: 74.5: 25.81
+	Hs
		1020249 PABP4_HUMAN (4-156): 2.89e-27: 107: 17.18		ELAV2_HUMAN (150-210): 9.69e-14: 74.5: 25.81
+	Hs
		516674 PABP1_HUMAN (4-156): 7.45e-28: 109: 18.41		RBM4_HUMAN (75-182): 7.64e-09: 59.3: 35.71