HitPredict

Interactor 1: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Interactor 2: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 603 Hs			1 246
+	Hs
		861687 PLK1_HUMAN (1-603): 0: 617: 100.00		1433E_HUMAN (1-244): 1.37e-141: 398: 62.71
+	Hs
		861686 PLK1_HUMAN (1-603): 0: 617: 100.00		1433G_HUMAN (1-246): 9.38e-138: 388: 86.99
+	Hs
		683915 PLK1_HUMAN (1-603): 0: 617: 100.00		1433S_HUMAN (3-245): 2.76e-96: 283: 64.20
+	Hs
		910097 PLK2_HUMAN (38-587): 7.26e-163: 482: 36.69		1433E_HUMAN (1-244): 1.37e-141: 398: 62.71
+	At
		965291 CDPK1_ARATH (1-498): 7.83e-155: 459: 22.09		14332_ARATH (4-244): 8.72e-141: 396: 60.91
+	At
		802001 CDPK1_ARATH (1-498): 7.83e-155: 459: 22.09		14334_ARATH (4-244): 5.36e-139: 392: 60.49
+	Ce
		711543 PLK1_CAEEL (22-599): 0: 536: 50.58		14332_CAEEL (4-241): 1.43e-108: 314: 76.05
+	Ce
		711356 PLK1_CAEEL (22-599): 0: 536: 50.58		14331_CAEEL (5-246): 3.56e-101: 296: 74.49
+	At
		1280891 CIPKC_ARATH (25-356): 2.96e-134: 402: 27.76		14337_ARATH (2-244): 2.9e-141: 398: 59.18
+	At
		788672 CIPKC_ARATH (25-356): 2.96e-134: 402: 27.76		14333_ARATH (1-244): 1.01e-141: 398: 61.38
+	At
		965360 CIPKC_ARATH (25-356): 2.96e-134: 402: 27.76		14332_ARATH (4-244): 8.72e-141: 396: 60.91
+	Hs
		982585 KS6B2_HUMAN (53-412): 9.32e-134: 401: 24.66		1433F_HUMAN (1-246): 6.09e-136: 383: 100.00
+	Hs
		684360 PLK2_HUMAN (38-587): 7.26e-163: 482: 36.69		1433S_HUMAN (3-245): 2.76e-96: 283: 64.20
+	Hs
		904590 KS6A1_HUMAN (1-362): 5.61e-109: 345: 24.87		1433G_HUMAN (1-246): 9.38e-138: 388: 86.99
+	Hs
		982035 KS6A1_HUMAN (1-362): 5.61e-109: 345: 24.87		1433F_HUMAN (1-246): 6.09e-136: 383: 100.00
+	Hs
		647354 KS6B2_HUMAN (53-412): 9.32e-134: 401: 24.66		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		683368 KS6A1_HUMAN (1-362): 5.61e-109: 345: 24.87		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		646913 KS6A1_HUMAN (1-362): 5.61e-109: 345: 24.87		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Rn
		716565 KS6A1_RAT (1-321): 9.84e-109: 344: 25.53		1433B_RAT (3-245): 9.89e-106: 307: 74.69
+	Hs
		684052 KS6A2_HUMAN (1-367): 4.14e-105: 335: 22.43		1433S_HUMAN (3-245): 2.76e-96: 283: 64.20