Protein: LRAD4
Low-density lipoprotein receptor class A domain-containing protein 4

Gene: LRAD4, LDLRAD4
Organism: Homo sapiens
Interactions: 60
UniProt ID: O15165

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0010719 - negative regulation of epithelial to mesenchymal transition
GO:0016020 - membrane
GO:0030336 - negative regulation of cell migration
GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

131580

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

5

12

High-throughput

0.712

High

180994

D19L1
Protein C-mannosyl-transferase DPY19L1

4

1

High-throughput

0.691

High

181013

ITCH
E3 ubiquitin-protein ligase Itchy homolog

4

12

High-throughput

0.691

High

180988

SMAD3
Mothers against decapentaplegic homolog 3

3

1

High-throughput

0.667

High

180992

SMAD2
Mothers against decapentaplegic homolog 2

3

1

High-throughput

0.667

High

180995

MAGI3
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3

3

3

High-throughput

0.667

High

180999

UBR3
E3 ubiquitin-protein ligase UBR3

3

2

High-throughput

0.667

High

181010

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

3

1

High-throughput

0.667

High

181021

SMUF2
E3 ubiquitin-protein ligase SMURF2

3

12

High-throughput

0.667

High

181022

SMUF1
E3 ubiquitin-protein ligase SMURF1

3

12

High-throughput

0.667

High

180983

NEDD4
E3 ubiquitin-protein ligase NEDD4

5

12

High-throughput

0.652

High

181008

FLCN
Folliculin

3

0

High-throughput

0.638

High

181002

HECW1
E3 ubiquitin-protein ligase HECW1

4

12

High-throughput

0.630

High

181005

AN13A
Ankyrin repeat domain-containing protein 13A

4

1

High-throughput

0.630

High

181014

NED4L
E3 ubiquitin-protein ligase NEDD4-like

4

12

High-throughput

0.630

High

181019

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

4

12

High-throughput

0.630

High

181026

HECW2
E3 ubiquitin-protein ligase HECW2

4

12

High-throughput

0.630

High

180981

AVR2A
Activin receptor type-2A

3

1

High-throughput

0.609

High

180984

YAP1
Transcriptional coactivator YAP1

3

15

High-throughput

0.609

High

180986

KC1E
Casein kinase I isoform epsilon

3

1

High-throughput

0.609

High

180996

WWC2
Protein WWC2

3

14

High-throughput

0.609

High

181000

AN13D
Ankyrin repeat domain-containing protein 13D

3

1

High-throughput

0.609

High

181001

STXB4
Syntaxin-binding protein 4

3

1

High-throughput

0.609

High

181003

TAXB1
Tax1-binding protein 1

3

2

High-throughput

0.609

High

181004

UBR1
E3 ubiquitin-protein ligase UBR1

3

2

High-throughput

0.609

High

181015

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

3

3

High-throughput

0.609

High

181031

EPN1
Epsin-1

3

1

High-throughput

0.609

High

180974

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

2

1

High-throughput

0.606

High

180993

WASC4
WASH complex subunit 4

2

0

High-throughput

0.602

High

180982

CNDD3
Condensin-2 complex subunit D3

2

0

High-throughput

0.585

High

181007

ZDH22
Palmitoyltransferase ZDHHC22

2

0

High-throughput

0.580

High

180991

AVR2B
Activin receptor type-2B

2

1

High-throughput

0.558

High

181020

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

1

High-throughput

0.536

High

180977

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.513

High

180987

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

0

High-throughput

0.513

High

180978

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

1

High-throughput

0.479

High

180989

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

2

High-throughput

0.479

High

180979

FGFR1
Fibroblast growth factor receptor 1

1

0

High-throughput

0.458

High

180997

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.458

High

181006

CMTR1
Cap-specific mRNA

1

0

High-throughput

0.458

High

181027

KDIS
Kinase D-interacting substrate of 220 kDa

1

0

High-throughput

0.458

High

181030

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

0

High-throughput

0.458

High

180985

KC1D
Casein kinase I isoform delta

1

1

High-throughput

0.437

High

181009

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

1

1

High-throughput

0.437

High

180990

TUSC3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3

1

1

High-throughput

0.407

High

180998

D19L2
Probable C-mannosyltransferase DPY19L2

1

1

High-throughput

0.407

High

181023

CUED1
CUE domain-containing protein 1

4

0

High-throughput

0.360

High

181012

RNF31
E3 ubiquitin-protein ligase RNF31

3

0

High-throughput

0.347

High

181018

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

3

0

High-throughput

0.347

High

181025

VPS18
Vacuolar protein sorting-associated protein 18 homolog

3

0

High-throughput

0.347

High

181028

SUFU
Suppressor of fused homolog

3

0

High-throughput

0.347

High

181029

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

2

0

High-throughput

0.328

High

180980

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

2

0

High-throughput

0.318

High

181024

WWOX
WW domain-containing oxidoreductase

2

0

High-throughput

0.318

High

180973

GET3
ATPase GET3

2

0

High-throughput

0.316

High

180975

KTNA1
Katanin p60 ATPase-containing subunit A1

1

0

High-throughput

0.279

Low

181016

UIMC1
BRCA1-A complex subunit RAP80

1

0

High-throughput

0.279

Low

181017

RTF2
Replication termination factor 2

1

0

High-throughput

0.249

Low

181011

AP2C
Transcription factor AP-2 gamma

1

0

High-throughput

0.238

Low

180976

ATE1
Arginyl-tRNA--protein transferase 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025