Interactor 1: DAPK1 (P53355)
Death-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)
Gene: DAPK1

Interactor 2: FADD (Q13158)
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Growth-inhibiting gene 3 protein) (Mediator of receptor induced toxicity)
Gene: FADD

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 12911633, 15048887
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Death~Death, DED~Pkinase
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006915 - apoptotic process
GO:0008625 - extrinsic apoptotic signaling pathway via death domain receptors
GO:0043065 - positive regulation of apoptotic process
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1430
Hs

1 208
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Last updated: 15 Jul 2024