Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1
Interactor 2: TEAD2 (Q15562)
Transcriptional enhancer factor TEF-4 (TEA domain family member 2) (TEAD-2)
Gene: TEAD2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.977 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28205554, 26578655, 25973055, 28514442, 32296183, 33961781, 35140242, 20368466, 25751139, unassigned1304 |
| Identification Methods | fluorescent resonance energy transfer, affinity chromatography technology, two hybrid, proximity labelling technology, nuclear magnetic resonance, isothermal titration calorimetry, pull down, tandem affinity purification, anti tag coimmunoprecipitation, validated two hybrid and 2 others
more... |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | TEADIR3~YBD |
| Common GO terms | GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0001570 - vasculogenesis GO:0003143 - embryonic heart tube morphogenesis GO:0005634 - nucleus GO:0005654 - nucleoplasm and 10 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
