Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1
Interactor 2: TEAD3 (Q99594)
Transcriptional enhancer factor TEF-5 (DTEF-1) (TEA domain family member 3) (TEAD-3)
Gene: TEAD3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.92 | 1.00 | 0.961 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24366813, 35140242, 25796446, 27684187, 26933062, 24255178, 25751139, 28514442 |
| Identification Methods | affinity chromatography technology, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | TEADIR3~YBD |
| Common GO terms | GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005654 - nucleoplasm GO:0035329 - hippo signaling GO:0045944 - positive regulation of transcription by RNA polymerase II |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
