Interactor 1: IQGA1 (P46940)
Ras GTPase-activating-like protein IQGAP1 (p195)
Gene: IQGAP1

Interactor 2: IQGA2 (Q13576)
Ras GTPase-activating-like protein IQGAP2
Gene: IQGAP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~CH, IQ~IQ, RasGAP~RasGAP
Common GO terms GO:0005095 - GTPase inhibitor activity
GO:0005096 - GTPase activator activity
GO:0005516 - calmodulin binding
GO:0005547 - phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005737 - cytoplasm
and 10 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1657
Hs

1 1575
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Last updated: 11Aug2025