HitPredict

Interactor 1: PGTB2 (P53611)
Geranylgeranyl transferase type-2 subunit beta (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta)
Gene: RABGGTB

Interactor 2: PGTA (Q92696)
Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha)
Gene: RABGGTA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.950

The method score is based on:

Property Details
Experiments 32296183, 33961781, 35271311, 26186194, 28514442, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PPTA~Prenyltrans
Common GO terms GO:0004663 - Rab geranylgeranyltransferase activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005968 - Rab-protein geranylgeranyltransferase complex
GO:0007601 - visual perception
and 4 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 331
Hs

1 567
+ Rn
+ Dm
+ Hs
+ Sc
+ Dm
+ Ce
+ Hs
+ Rn
+ Hs
+ Rn
+ Dm
+ Sp
+ At
+ Sc
+ Sp
+ Sc
+ Ce
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024