HitPredict

Interactor 1: B9EKJ1 (B9EKJ1)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)
Gene: Sptan1

Interactor 2: TNIK (P83510)
Traf2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF-hand_7~Pkinase
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2477 Mm			1 1323
+	Mm
		597648 SPTN1_MOUSE (1-1982): 5.66e-64: 245: 19.55		TNIK_MOUSE (1-1323): 0: 1263: 100.00
+	Mm
		1013604 Q68FG2_MOUSE (5-1617): 2.2e-61: 236: 19.91		TNIK_MOUSE (1-1323): 0: 1263: 100.00
+	Hs
		1105676 GOGA4_HUMAN (2-1595): 8.52e-52: 205: 9.35		TNIK_HUMAN (1-1323): 0: 1231: 95.29
+	Mm
		1013598 SPTB2_MOUSE (1-1194): 8.15e-34: 146: 18.56		TNIK_MOUSE (1-1323): 0: 1263: 100.00
+	Hs
		1461052 MACF1_HUMAN (274-2421): 1.82e-36: 155: 9.46		TNIK_HUMAN (1-1323): 0: 1231: 95.29
+	Hs
		1028907 SPTB2_HUMAN (1-1105): 1.37e-33: 145: 19.31		TNIK_HUMAN (1-1323): 0: 1231: 95.29
+	Mm
		1013689 DYST_MOUSE (921-2456): 6.28e-19: 97.1: 10.20		TNIK_MOUSE (1-1323): 0: 1263: 100.00
+	Mm
		1013714 MACF1_MOUSE (813-2411): 9.23e-15: 83.6: 9.21		TNIK_MOUSE (1-1323): 0: 1263: 100.00
+	Hs
		1040399 DYST_HUMAN (252-1199): 1.82e-12: 75.9: 10.87		TNIK_HUMAN (1-1323): 0: 1231: 95.29
+	Hs
		1414958 CP250_HUMAN (5-2204): 1.06e-72: 273: 9.44		SIK2_HUMAN (15-898): 1.44e-128: 422: 13.96
+	Hs
		1093102 SPTN1_HUMAN (1-1982): 1.05e-63: 244: 19.50		STK4_HUMAN (5-470): 4.38e-119: 381: 32.59
+	Hs
		692161 MACF1_HUMAN (274-2421): 1.82e-36: 155: 9.46		MARK3_HUMAN (3-717): 3.48e-125: 407: 16.08
+	Hs
		1028753 SPTB2_HUMAN (1-1105): 1.37e-33: 145: 19.31		STK3_HUMAN (4-496): 1.5e-117: 377: 30.12
+	Hs
		563052 MYH8_HUMAN (1543-2460): 7.85e-32: 139: 11.05		STK4_HUMAN (5-470): 4.38e-119: 381: 32.59
+	Hs
		563053 MYH8_HUMAN (1543-2460): 7.85e-32: 139: 11.05		STK3_HUMAN (4-496): 1.5e-117: 377: 30.12
+	Mm
		267277 DYST_MOUSE (921-2456): 6.28e-19: 97.1: 10.20		CSKP_MOUSE (22-704): 3.43e-124: 410: 15.75
+	Hs
		1093204 MYH2_HUMAN (1891-2423): 4.11e-15: 84.4: 12.55		STK4_HUMAN (5-470): 4.38e-119: 381: 32.59
+	Hs
		1097759 MYH2_HUMAN (1891-2423): 4.11e-15: 84.4: 12.55		STK3_HUMAN (4-496): 1.5e-117: 377: 30.12
+	Hs
		556920 MYH7_HUMAN (1914-2416): 2.55e-12: 75.1: 10.54		STK4_HUMAN (5-470): 4.38e-119: 381: 32.59
+	Hs
		1040281 DYST_HUMAN (252-1199): 1.82e-12: 75.9: 10.87		STK3_HUMAN (4-496): 1.5e-117: 377: 30.12