HitPredict

Interactor 1: SPTN1 (P16546)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)
Gene: Sptan1

Interactor 2: TNIK (P83510)
Traf2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	28671696
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	EF-hand_7~Pkinase
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2472 Mm			1 1323
+	Mm
		1013598 SPTB2_MOUSE (1-1503): 1.67e-66: 253: 22.48		TNIK_MOUSE (1-1323): 0: 1263: 100.00
+	Mm
		1013604 Q68FG2_MOUSE (1-1506): 4.88e-58: 225: 23.62		TNIK_MOUSE (1-1323): 0: 1263: 100.00
+	Hs
		1028907 SPTB2_HUMAN (1-1503): 4.96e-67: 255: 22.48		TNIK_HUMAN (1-1323): 0: 1231: 95.29
+	Mm
		1013567 Q155P7_MOUSE (126-2454): 3.83e-51: 203: 9.13		TNIK_MOUSE (1-1323): 0: 1263: 100.00
+	Mm
		97921 E9Q3P4_MOUSE (126-2454): 4.24e-51: 203: 9.13		TNIK_MOUSE (1-1323): 0: 1263: 100.00
+	Mm
		86342 B9EKJ1_MOUSE (2-1101): 1e-37: 159: 22.34		TNIK_MOUSE (1-1323): 0: 1263: 100.00
+	Mm
		1013714 MACF1_MOUSE (807-2446): 1.5e-20: 102: 9.16		TNIK_MOUSE (1-1323): 0: 1263: 100.00
+	Hs
		1461052 MACF1_HUMAN (4-1586): 7.47e-24: 113: 13.88		TNIK_HUMAN (1-1323): 0: 1231: 95.29
+	Hs
		1105676 GOGA4_HUMAN (1859-2461): 2.26e-13: 78.6: 10.25		TNIK_HUMAN (1-1323): 0: 1231: 95.29
+	Hs
		1040399 DYST_HUMAN (236-1219): 1.06e-11: 73.2: 10.37		TNIK_HUMAN (1-1323): 0: 1231: 95.29
+	Mm
		1021940 CE290_MOUSE (156-2457): 1.25e-54: 214: 9.92		M4K4_MOUSE (1-1323): 0: 981: 60.65
+	Hs
		1414958 CP250_HUMAN (153-2350): 1.26e-75: 283: 10.39		SIK2_HUMAN (15-898): 1.44e-128: 422: 13.96
+	Hs
		1028753 SPTB2_HUMAN (1-1503): 4.96e-67: 255: 22.48		STK3_HUMAN (4-496): 1.5e-117: 377: 30.12
+	Hs
		1093102 SPTN1_HUMAN (2-1101): 1.58e-38: 161: 22.69		STK4_HUMAN (5-470): 4.38e-119: 381: 32.59
+	Hs
		1093204 MYH2_HUMAN (1401-2411): 1.65e-33: 144: 10.73		STK4_HUMAN (5-470): 4.38e-119: 381: 32.59
+	Hs
		547463 DMD_HUMAN (952-2365): 2.82e-20: 101: 12.52		MARK2_HUMAN (8-709): 3.78e-130: 422: 17.94
+	Hs
		1097759 MYH2_HUMAN (1401-2411): 1.65e-33: 144: 10.73		STK3_HUMAN (4-496): 1.5e-117: 377: 30.12
+	Hs
		692161 MACF1_HUMAN (4-1586): 7.47e-24: 113: 13.88		MARK3_HUMAN (3-717): 3.48e-125: 407: 16.08
+	Hs
		168623 DMD_HUMAN (952-2365): 2.82e-20: 101: 12.52		CSKP_HUMAN (22-702): 4.13e-125: 412: 15.80
+	Hs
		1040281 DYST_HUMAN (236-1219): 1.06e-11: 73.2: 10.37		STK3_HUMAN (4-496): 1.5e-117: 377: 30.12