HitPredict

Interactor 1: RPGP1 (P47736)
Rap1 GTPase-activating protein 1 (Rap1GAP) (Rap1GAP1)
Gene: RAP1GAP

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	36931259, 15161933
Identification Methods	proximity labelling technology, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 663 Hs			1 245
+	Hs
		866518 RPGP1_HUMAN (1-663): 0: 911: 100.00		1433E_HUMAN (2-241): 9.95e-144: 403: 68.18
+	Hs
		690820 RPGP1_HUMAN (1-663): 0: 911: 100.00		1433T_HUMAN (1-245): 2.61e-140: 395: 79.59
+	Hs
		729671 RPGP1_HUMAN (1-663): 0: 911: 100.00		1433B_HUMAN (1-242): 9.05e-140: 393: 87.60
+	Hs
		866517 RPGP1_HUMAN (1-663): 0: 911: 100.00		1433G_HUMAN (1-240): 2.38e-108: 314: 74.59
+	Hs
		866522 RPGP1_HUMAN (1-663): 0: 911: 100.00		1433F_HUMAN (2-240): 1.27e-107: 312: 74.49
+	Hs
		730443 RPGP1_HUMAN (1-663): 0: 911: 100.00		1433S_HUMAN (1-237): 8.31e-104: 302: 71.97
+	Hs
		990343 RPGP2_HUMAN (1-632): 0: 782: 53.39		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		971635 RPGP2_HUMAN (1-632): 0: 782: 53.39		1433E_HUMAN (2-241): 9.95e-144: 403: 68.18
+	Hs
		990820 SI1L2_HUMAN (54-401): 4.5e-143: 458: 35.33		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		972088 SI1L2_HUMAN (54-401): 4.5e-143: 458: 35.33		1433E_HUMAN (2-241): 9.95e-144: 403: 68.18
+	Hs
		691503 SI1L2_HUMAN (54-401): 4.5e-143: 458: 35.33		1433T_HUMAN (1-245): 2.61e-140: 395: 79.59
+	Hs
		730314 SI1L2_HUMAN (54-401): 4.5e-143: 458: 35.33		1433B_HUMAN (1-242): 9.05e-140: 393: 87.60
+	Hs
		244561 SI1L3_HUMAN (45-400): 1.91e-135: 438: 35.56		1433E_HUMAN (2-241): 9.95e-144: 403: 68.18
+	Hs
		244536 SI1L3_HUMAN (45-400): 1.91e-135: 438: 35.56		1433T_HUMAN (1-245): 2.61e-140: 395: 79.59
+	Hs
		244538 SI1L3_HUMAN (45-400): 1.91e-135: 438: 35.56		1433B_HUMAN (1-242): 9.05e-140: 393: 87.60
+	Hs
		966971 SI1L2_HUMAN (54-401): 4.5e-143: 458: 35.33		1433G_HUMAN (1-240): 2.38e-108: 314: 74.59
+	Hs
		1049863 SI1L2_HUMAN (54-401): 4.5e-143: 458: 35.33		1433F_HUMAN (2-240): 1.27e-107: 312: 74.49
+	Hs
		730935 SI1L2_HUMAN (54-401): 4.5e-143: 458: 35.33		1433S_HUMAN (1-237): 8.31e-104: 302: 71.97
+	Hs
		244559 SI1L3_HUMAN (45-400): 1.91e-135: 438: 35.56		1433G_HUMAN (1-240): 2.38e-108: 314: 74.59
+	Hs
		244539 SI1L3_HUMAN (45-400): 1.91e-135: 438: 35.56		1433S_HUMAN (1-237): 8.31e-104: 302: 71.97