HitPredict

Interactor 1: VGFR2 (P35968)
Vascular endothelial growth factor receptor 2 (VEGFR-2) (EC 2.7.10.1) (Fetal liver kinase 1) (FLK-1) (Kinase insert domain receptor) (KDR) (Protein-tyrosine kinase receptor flk-1) (CD antigen CD309)
Gene: KDR

Interactor 2: DDX54 (Q8TDD1)
ATP-dependent RNA helicase DDX54 (EC 3.6.4.13) (ATP-dependent RNA helicase DP97) (DEAD box RNA helicase 97 kDa) (DEAD box protein 54)
Gene: DDX54

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005794 - Golgi apparatus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1356 Hs			1 881
+	Hs
		729680 VGFR2_HUMAN (1-1356): 0: 1028: 100.00		DDX27_HUMAN (98-446): 2.63e-60: 221: 41.24
+	Hs
		572659 VGFR1_HUMAN (1-131): 5.1e-20: 99.3: 13.38		DDX54_HUMAN (1-881): 0: 626: 100.00
+	Hs
		738242 FLT3_HUMAN (40-555): 7.17e-20: 98.5: 16.22		DDX54_HUMAN (1-881): 0: 626: 100.00
+	Hs
		609440 FGFR3_HUMAN (1-120): 8.75e-18: 91.6: 16.90		DDX54_HUMAN (1-881): 0: 626: 100.00
+	Hs
		729315 VGFR3_HUMAN (1-123): 1.31e-13: 78.1: 14.93		DDX54_HUMAN (1-881): 0: 626: 100.00
+	Hs
		601566 FGFR2_HUMAN (1-231): 3.47e-24: 112: 9.57		DDX27_HUMAN (98-446): 2.63e-60: 221: 41.24
+	Hs
		572670 VGFR1_HUMAN (1-131): 5.1e-20: 99.3: 13.38		DDX27_HUMAN (98-446): 2.63e-60: 221: 41.24
+	Hs
		738255 FLT3_HUMAN (40-555): 7.17e-20: 98.5: 16.22		DDX27_HUMAN (98-446): 2.63e-60: 221: 41.24
+	Hs
		609477 FGFR3_HUMAN (1-120): 8.75e-18: 91.6: 16.90		DDX27_HUMAN (98-446): 2.63e-60: 221: 41.24
+	Hs
		572679 VGFR1_HUMAN (1-131): 5.1e-20: 99.3: 13.38		DDX47_HUMAN (91-461): 3.97e-56: 202: 33.42
+	Hs
		738267 FLT3_HUMAN (40-555): 7.17e-20: 98.5: 16.22		DDX47_HUMAN (91-461): 3.97e-56: 202: 33.42
+	Hs
		729334 VGFR3_HUMAN (1-123): 1.31e-13: 78.1: 14.93		DDX27_HUMAN (98-446): 2.63e-60: 221: 41.24
+	Hs
		609525 FGFR3_HUMAN (1-120): 8.75e-18: 91.6: 16.90		DDX47_HUMAN (91-461): 3.97e-56: 202: 33.42
+	Hs
		729352 VGFR3_HUMAN (1-123): 1.31e-13: 78.1: 14.93		DDX47_HUMAN (91-461): 3.97e-56: 202: 33.42