HitPredict

Interactor 1: BLM (P54132)
RecQ-like DNA helicase BLM (EC 5.6.2.4) (Bloom syndrome protein) (DNA 3'-5' helicase BLM) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3)
Gene: BLM

Interactor 2: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1417 Hs			1 126
+	Hs
		867561 BLM_HUMAN (1-1417): 0: 898: 100.00		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		295518 RECQ5_HUMAN (646-1075): 4.96e-148: 478: 39.15		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		801847 RECQ1_HUMAN (626-1233): 2.63e-131: 422: 34.75		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		801892 RECQ1_HUMAN (626-1233): 2.63e-131: 422: 34.75		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		801940 RECQ1_HUMAN (626-1233): 2.63e-131: 422: 34.75		H2B1L_HUMAN (1-126): 2.49e-52: 162: 97.62
+	Hs
		294653 RECQ4_HUMAN (661-1003): 2.2e-43: 175: 34.80		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		294440 RECQ4_HUMAN (661-1003): 2.2e-43: 175: 34.80		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Hs
		295092 RECQ4_HUMAN (661-1003): 2.2e-43: 175: 34.80		H2B1A_HUMAN (1-126): 3.43e-46: 147: 85.04