HitPredict

Interactor 1: MLC2 (P54357)
Myosin-2 essential light chain (Myosin II essential light chain) (Non-muscle myosin essential light chain)
Gene: Mlc-c

Interactor 2: MYS9 (Q01989)
Myosin heavy chain 95F (95F MHC) (Protein jaguar)
Gene: jar

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	16917818
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF-hand_6~Myosin_head, EF-hand_7~Myosin_head, EF-hand_7~Myosin_N
Common GO terms	GO:0030048 - actin filament-based movement GO:0031476 - myosin VI complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Dm			1 1253
+	Dm
		906662 CALM_DROME (3-146): 1.12e-46: 149: 43.45		MYS9_DROME (1-1253): 0: 981: 100.00
+	Hs
		538709 MYL6B_HUMAN (3-146): 1.59e-47: 154: 53.38		MYO6_HUMAN (2-1245): 0: 886: 49.03
+	Hs
		483966 CALM1_HUMAN (3-146): 3.02e-47: 151: 43.45		MYO6_HUMAN (2-1245): 0: 886: 49.03
+	Hs
		484047 CALM2_HUMAN (3-146): 3.02e-47: 151: 43.45		MYO6_HUMAN (2-1245): 0: 886: 49.03
+	Hs
		484219 CALM3_HUMAN (3-146): 3.02e-47: 151: 43.45		MYO6_HUMAN (2-1245): 0: 886: 49.03
+	Sc
		420253 CALM_YEAST (2-146): 1.14e-45: 147: 37.42		MYO4_YEAST (2-1036): 0: 886: 26.18
+	Ss
		94703 F2Z5G3_PIG (3-146): 3.02e-47: 151: 43.45		MYO6_PIG (2-1245): 0: 880: 50.20
+	Dm
		906697 CALM_DROME (3-146): 1.12e-46: 149: 43.45		MYO7A_DROME (1-974): 0: 879: 29.93
+	Dm
		870146 MLC2_DROME (1-147): 9.93e-45: 144: 100.00		MYO7A_DROME (1-974): 0: 879: 29.93
+	Hs
		484202 CALM3_HUMAN (3-146): 3.02e-47: 151: 43.45		MYO10_HUMAN (2-1031): 0: 848: 29.94
+	Hs
		648611 CALL3_HUMAN (3-146): 5.6e-44: 143: 41.38		MYO10_HUMAN (2-1031): 0: 848: 29.94
+	Hs
		214479 CALM1_HUMAN (3-146): 3.02e-47: 151: 43.45		MYO1B_HUMAN (68-826): 1.18e-128: 426: 35.60
+	Hs
		214480 CALM3_HUMAN (3-146): 3.02e-47: 151: 43.45		MYO1B_HUMAN (68-826): 1.18e-128: 426: 35.60
+	Hs
		484206 CALM3_HUMAN (3-146): 3.02e-47: 151: 43.45		MYO5C_HUMAN (699-1185): 2.7e-25: 116: 10.00
+	Hs
		484218 CALM3_HUMAN (3-146): 3.02e-47: 151: 43.45		MYO5B_HUMAN (666-1156): 3.11e-14: 80.4: 9.35
+	Hs
		538642 MYL6B_HUMAN (3-146): 1.59e-47: 154: 53.38		MYH9_HUMAN (755-1145): 1.05e-09: 65.5: 12.31
+	Hs
		724737 MYL6_HUMAN (1-147): 1.81e-45: 147: 53.64		MYH9_HUMAN (755-1145): 1.05e-09: 65.5: 12.31
+	Sc
		420223 CALM_YEAST (2-146): 1.14e-45: 147: 37.42		MYO2_YEAST (1027-1250): 1.3e-09: 65: 7.46
+	Hs
		648467 CALL3_HUMAN (3-146): 5.6e-44: 143: 41.38		MYH9_HUMAN (755-1145): 1.05e-09: 65.5: 12.31
+	Hs
		441665 MYL3_HUMAN (4-146): 8.71e-40: 134: 48.99		MYH9_HUMAN (755-1145): 1.05e-09: 65.5: 12.31