HitPredict

Interactor 1: FKB12 (P48375)
Peptidyl-prolyl cis-trans isomerase Fkbp12 (PPIase Fkbp12) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (Macrolide-binding protein) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase)
Gene: Fkbp12

Interactor 2: Q9VAY2 (Q9VAY2)
Heat shock protein 83 (HSP 82)
Gene: Gp93

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	FKBP_C~HSP90
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 108 Dm			1 787
+	Dm
		1464321 Q9V3V2_DROME (3-107): 1.17e-48: 155: 48.60		Q9VAY2_DROME (1-787): 0: 967: 100.00
+	Hs
		461340 FKB1A_HUMAN (1-108): 1.1e-52: 162: 75.93		HS90A_HUMAN (69-786): 0: 950: 43.89
+	Dm
		1468637 Q9VGK3_DROME (1-108): 6.87e-43: 138: 41.28		Q9VAY2_DROME (1-787): 0: 967: 100.00
+	Hs
		117613 FKBP6_HUMAN (2-107): 3.57e-40: 137: 33.65		K9JA46_HUMAN (69-786): 0: 950: 43.89
+	Hs
		276661 FKBP6_HUMAN (2-107): 3.57e-40: 137: 33.65		HS90A_HUMAN (69-786): 0: 950: 43.89
+	Hs
		276662 FKBP6_HUMAN (2-107): 3.57e-40: 137: 33.65		HS90B_HUMAN (74-786): 0: 944: 43.41
+	Dm
		1468654 FKB59_DROME (3-106): 9.98e-15: 70.1: 24.07		Q9VAY2_DROME (1-787): 0: 967: 100.00
+	Hs
		117619 FKBP4_HUMAN (2-108): 5.65e-15: 70.9: 27.93		K9JA46_HUMAN (69-786): 0: 950: 43.89
+	Hs
		461376 FKBP4_HUMAN (2-108): 5.65e-15: 70.9: 27.93		HS90A_HUMAN (69-786): 0: 950: 43.89
+	Hs
		117620 FKBP5_HUMAN (2-108): 2.99e-14: 68.6: 27.93		K9JA46_HUMAN (69-786): 0: 950: 43.89
+	Hs
		461443 FKBP5_HUMAN (2-108): 2.99e-14: 68.6: 27.93		HS90A_HUMAN (69-786): 0: 950: 43.89
+	Mm
		462098 FKBP4_MOUSE (2-108): 5.02e-15: 70.9: 27.93		HS90A_MOUSE (69-786): 0: 947: 43.69
+	Hs
		468282 FKBP4_HUMAN (2-108): 5.65e-15: 70.9: 27.93		HS90B_HUMAN (74-786): 0: 944: 43.41
+	Hs
		468336 FKBP5_HUMAN (2-108): 2.99e-14: 68.6: 27.93		HS90B_HUMAN (74-786): 0: 944: 43.41
+	At
		690686 FKB62_ARATH (2-108): 3.5e-20: 85.5: 28.57		HS901_ARATH (71-772): 0: 922: 47.95
+	Sc
		578822 FKBP_YEAST (3-107): 8.74e-49: 152: 62.86		HSC82_YEAST (72-783): 0: 840: 46.19
+	Sc
		392208 FKBP_YEAST (3-107): 8.74e-49: 152: 62.86		HSP82_YEAST (72-783): 0: 838: 45.79
+	Ce
		233841 O45418_CAEEL (3-108): 2.41e-10: 57.4: 27.93		HSP90_CAEEL (68-778): 0: 904: 45.44