HitPredict

Interactor 1: EPHA4 (P54764)
Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)
Gene: EPHA4

Interactor 2: LR74A (Q0VAA2)
Leucine-rich repeat-containing protein 74A (Leucine-rich repeat-containing protein 74)
Gene: LRRC74A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 986 Hs			1 488
+	At
		1278223 BAK1_ARATH (344-927): 2.63e-150: 460: 16.45		IRK_ARATH (1-456): 6.35e-61: 216: 14.15
+	At
		1278209 BAK1_ARATH (344-927): 2.63e-150: 460: 16.45		FLS2_ARATH (41-485): 3.22e-52: 192: 13.67
+	At
		84479 BAK1_ARATH (344-927): 2.63e-150: 460: 16.45		GSO1_ARATH (1-399): 1.79e-51: 190: 13.68
+	At
		84744 BAK1_ARATH (344-927): 2.63e-150: 460: 16.45		Y4361_ARATH (1-358): 1.45e-49: 184: 12.47
+	At
		1013318 Y2239_ARATH (370-959): 4.92e-150: 460: 16.27		CEPR2_ARATH (1-386): 2.28e-49: 183: 14.91
+	At
		83975 BAK1_ARATH (344-927): 2.63e-150: 460: 16.45		Y1743_ARATH (1-391): 3.29e-46: 174: 12.88
+	At
		1278242 BAK1_ARATH (344-927): 2.63e-150: 460: 16.45		BRL1_ARATH (2-377): 1.12e-45: 173: 14.10
+	At
		1013320 Y2239_ARATH (370-959): 4.92e-150: 460: 16.27		TDR_ARATH (165-482): 3.57e-36: 144: 10.28
+	At
		1278216 BAK1_ARATH (344-927): 2.63e-150: 460: 16.45		BRL3_ARATH (2-361): 8.11e-36: 143: 12.34
+	At
		1167621 BAK1_ARATH (344-927): 2.63e-150: 460: 16.45		ERL2_ARATH (1-325): 5.94e-33: 134: 15.63
+	At
		1114696 BAK1_ARATH (344-927): 2.63e-150: 460: 16.45		ERECT_ARATH (191-487): 5.14e-30: 126: 15.58
+	At
		84592 Y2239_ARATH (370-959): 4.92e-150: 460: 16.27		RGI3_ARATH (208-487): 3.58e-25: 111: 12.37
+	At
		84597 BAK1_ARATH (344-927): 2.63e-150: 460: 16.45		RGI3_ARATH (208-487): 3.58e-25: 111: 12.37
+	At
		99017 BAK1_ARATH (344-927): 2.63e-150: 460: 16.45		RGI4_ARATH (156-487): 3.71e-25: 111: 10.48
+	At
		83680 Y2239_ARATH (370-959): 4.92e-150: 460: 16.27		RGI5_ARATH (1-180): 1.4e-23: 106: 11.11
+	At
		287460 Y2239_ARATH (370-959): 4.92e-150: 460: 16.27		SKM1_ARATH (272-487): 9.36e-19: 91.8: 13.10
+	At
		287464 BAK1_ARATH (344-927): 2.63e-150: 460: 16.45		SKM1_ARATH (272-487): 9.36e-19: 91.8: 13.10
+	At
		85361 BAK1_ARATH (344-927): 2.63e-150: 460: 16.45		ERL1_ARATH (1-179): 5.53e-18: 89.1: 12.02
+	At
		1013322 Y2239_ARATH (370-959): 4.92e-150: 460: 16.27		PEPR2_ARATH (1-161): 3.59e-14: 77.2: 10.43
+	At
		1278213 BAK1_ARATH (344-927): 2.63e-150: 460: 16.45		PEPR2_ARATH (1-161): 3.59e-14: 77.2: 10.43