HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: ATD3A (Q9NVI7)
ATPase family AAA domain-containing protein 3A (EC 3.6.1.-)
Gene: ATAD3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.50	0.543

Property	Details
Experiments	35140242, 34732716
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 586
+	Hs
		872415 SOX2_HUMAN (1-317): 7.52e-76: 236: 100.00		ATD3B_HUMAN (41-586): 4.07e-118: 366: 93.41
+	Mm
		873037 SOX2_MOUSE (1-317): 2.25e-70: 223: 94.67		ATD3A_MOUSE (1-585): 1.93e-109: 341: 91.45
+	Hs
		872161 SOX2_HUMAN (1-317): 7.52e-76: 236: 100.00		PRS10_HUMAN (172-574): 1.01e-100: 312: 16.59
+	Hs
		776134 SOX5_HUMAN (2-127): 7.95e-43: 158: 41.27		ATD3A_HUMAN (41-586): 7.3e-114: 353: 100.00
+	Hs
		240005 SOX15_HUMAN (13-118): 1.79e-31: 119: 66.04		ATD3A_HUMAN (41-586): 7.3e-114: 353: 100.00
+	Hs
		776256 SOX6_HUMAN (29-246): 1.78e-28: 117: 23.39		ATD3A_HUMAN (41-586): 7.3e-114: 353: 100.00
+	Hs
		188521 CIC_HUMAN (3-272): 4.72e-28: 116: 19.08		NVL_HUMAN (1-256): 1.25e-35: 144: 10.73