HitPredict

Interactor 1: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Interactor 2: RC3H2 (Q9HBD1)
Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)
Gene: RC3H2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30209976, 29395067
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2157 Hs			1 1191
+	Hs
		1206548 PRC2B_HUMAN (1-2145): 3.28e-71: 268: 21.86		RC3H2_HUMAN (1-1191): 0: 1091: 100.00
+	Hs
		875686 PRC2A_HUMAN (1-2157): 2.13e-162: 555: 100.00		RC3H1_HUMAN (1-1101): 0: 764: 49.34
+	Hs
		1311408 ANKH1_HUMAN (88-992): 3.87e-34: 146: 14.15		RC3H2_HUMAN (1-1191): 0: 1091: 100.00
+	Hs
		1206464 PRC2B_HUMAN (1-2145): 3.28e-71: 268: 21.86		RC3H1_HUMAN (1-1101): 0: 764: 49.34
+	Hs
		1215699 ANKH1_HUMAN (88-992): 3.87e-34: 146: 14.15		RC3H1_HUMAN (1-1101): 0: 764: 49.34
+	Hs
		1215900 SRRM2_HUMAN (1254-2153): 1.15e-14: 82.8: 10.10		RC3H1_HUMAN (1-1101): 0: 764: 49.34
+	Hs
		274117 PRC2A_HUMAN (1-2157): 2.13e-162: 555: 100.00		ANR17_HUMAN (349-895): 5.78e-13: 76.2: 10.40
+	Hs
		274155 PRC2B_HUMAN (1-2145): 3.28e-71: 268: 21.86		ANR17_HUMAN (349-895): 5.78e-13: 76.2: 10.40
+	Hs
		590235 MUC1_HUMAN (1250-2151): 4.19e-60: 230: 13.22		MUC1_HUMAN (344-859): 9.41e-17: 88.2: 9.85
+	Hs
		349180 TITIN_HUMAN (25-1276): 1.77e-18: 95.6: 10.03		LATS1_HUMAN (326-929): 8.44e-29: 127: 9.31
+	Hs
		274188 ANKH1_HUMAN (88-992): 3.87e-34: 146: 14.15		ANR17_HUMAN (349-895): 5.78e-13: 76.2: 10.40
+	Hs
		349296 SRRM2_HUMAN (1254-2153): 1.15e-14: 82.8: 10.10		LATS1_HUMAN (326-929): 8.44e-29: 127: 9.31
+	Hs
		1401422 CIC_HUMAN (214-2122): 2.45e-25: 117: 9.87		CHD7_HUMAN (489-1021): 3.52e-12: 73.5: 6.93
+	Hs
		925743 CIC_HUMAN (214-2122): 2.45e-25: 117: 9.87		SC24C_HUMAN (362-642): 2.35e-09: 63.8: 12.98
+	Hs
		161491 KMT2C_HUMAN (660-2157): 9.75e-16: 86.3: 8.91		KMT2D_HUMAN (403-1074): 2.75e-11: 70.8: 9.38
+	Hs
		1129637 MICA3_HUMAN (304-1107): 1.12e-14: 82.7: 12.18		MDC1_HUMAN (442-806): 1.15e-11: 71.8: 12.21
+	Hs
		1129588 MDC1_HUMAN (912-2156): 2.06e-14: 81.8: 10.35		MDC1_HUMAN (442-806): 1.15e-11: 71.8: 12.21
+	Hs
		274266 PRC2C_HUMAN (256-2153): 5.31e-13: 77.4: 8.33		ANR17_HUMAN (349-895): 5.78e-13: 76.2: 10.40
+	Hs
		1129671 MDC1_HUMAN (912-2156): 2.06e-14: 81.8: 10.35		CBP_HUMAN (603-1030): 1.32e-10: 68.1: 8.88
+	Hs
		334311 TACC2_HUMAN (43-1390): 3.53e-14: 81.3: 9.70		CBP_HUMAN (603-1030): 1.32e-10: 68.1: 8.88