HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (EC 3.6.1.-) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.925

Property	Details
Experiments	25342745, 28514442, 27705803, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 342
+	Hs
		881860 TCPG_HUMAN (14-540): 0: 574: 33.15		DCAF7_HUMAN (1-342): 2.52e-86: 265: 100.00
+	Hs
		964724 TCPH_HUMAN (12-539): 0: 572: 29.64		DCAF7_HUMAN (1-342): 2.52e-86: 265: 100.00
+	Hs
		142300 TCPE_HUMAN (1-541): 0: 637: 100.00		PEX7_HUMAN (20-341): 4.04e-59: 194: 17.90
+	Ce
		866358 TCPE_CAEEL (3-540): 0: 587: 68.40		LIN53_CAEEL (10-342): 7.02e-69: 223: 14.63
+	Hs
		142302 TCPG_HUMAN (14-540): 0: 574: 33.15		PEX7_HUMAN (20-341): 4.04e-59: 194: 17.90
+	Hs
		142403 TCPH_HUMAN (12-539): 0: 572: 29.64		PEX7_HUMAN (20-341): 4.04e-59: 194: 17.90
+	Hs
		875898 TCPE_HUMAN (1-541): 0: 637: 100.00		WDR5_HUMAN (208-342): 1.41e-28: 114: 11.85
+	Hs
		876070 TCPE_HUMAN (1-541): 0: 637: 100.00		POC1A_HUMAN (2-204): 3.35e-28: 114: 18.72
+	Hs
		876145 TCPE_HUMAN (1-541): 0: 637: 100.00		GRWD1_HUMAN (125-326): 1.98e-23: 102: 22.62
+	Hs
		876081 TCPE_HUMAN (1-541): 0: 637: 100.00		POC1B_HUMAN (3-194): 1.26e-20: 94.1: 8.25
+	Hs
		876199 TCPE_HUMAN (1-541): 0: 637: 100.00		NLE1_HUMAN (249-341): 1.99e-20: 93.7: 15.05
+	Hs
		875977 TCPE_HUMAN (1-541): 0: 637: 100.00		RBBP7_HUMAN (2-153): 4.87e-15: 77.5: 15.72
+	At
		146738 TCPE_ARATH (6-538): 0: 608: 68.29		PEX7_ARATH (125-342): 9.4e-25: 104: 16.74
+	Hs
		845257 TCPG_HUMAN (14-540): 0: 574: 33.15		LIS1_HUMAN (153-340): 1.08e-36: 138: 12.23
+	Hs
		881861 TCPG_HUMAN (14-540): 0: 574: 33.15		WDR5_HUMAN (208-342): 1.41e-28: 114: 11.85
+	Hs
		882038 TCPG_HUMAN (14-540): 0: 574: 33.15		POC1A_HUMAN (2-204): 3.35e-28: 114: 18.72
+	Hs
		882014 TCPG_HUMAN (14-540): 0: 574: 33.15		WDR5B_HUMAN (206-342): 1.98e-25: 106: 12.41
+	Sc
		811594 TCPE_YEAST (3-540): 0: 583: 59.89		PEX7_YEAST (20-297): 1.92e-21: 95.6: 20.57
+	Hs
		882118 TCPG_HUMAN (14-540): 0: 574: 33.15		GRWD1_HUMAN (125-326): 1.98e-23: 102: 22.62
+	Hs
		882051 TCPG_HUMAN (14-540): 0: 574: 33.15		POC1B_HUMAN (3-194): 1.26e-20: 94.1: 8.25