HitPredict

Interactor 1: DSRAD (P55265)
Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP)
Gene: ADAR

Interactor 2: DSRAD (P55265)
Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP)
Gene: ADAR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.873

The method score is based on:

Property Details
Experiments 32433965, 17428802, 17437712, 23622242
Identification Methods proximity labelling technology, affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains A_deamin~A_deamin, A_deamin~dsrm, dsrm~dsrm, z-alpha~z-alpha
Common GO terms GO:0001649 - osteoblast differentiation
GO:0002244 - hematopoietic progenitor cell differentiation
GO:0002566 - somatic diversification of immune receptors via somatic mutation
GO:0003677 - DNA binding
GO:0003723 - RNA binding
and 33 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024