HitPredict

Interactor 1: CADH4 (P55283)
Cadherin-4 (Retinal cadherin) (R-CAD) (R-cadherin)
Gene: CDH4

Interactor 2: CTNA3 (Q9UI47)
Catenin alpha-3 (Alpha T-catenin) (Cadherin-associated protein)
Gene: CTNNA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005912 - adherens junction GO:0045296 - cadherin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 916 Hs			1 895
+	Hs
		522254 CADH1_HUMAN (26-916): 0: 728: 42.59		CTNA3_HUMAN (1-895): 0: 1016: 100.00
+	Hs
		521735 CADH1_HUMAN (26-916): 0: 728: 42.59		CTNA2_HUMAN (2-891): 0: 1002: 57.66
+	Hs
		521757 CADH1_HUMAN (26-916): 0: 728: 42.59		CTNA1_HUMAN (7-891): 0: 992: 59.40
+	Mm
		454942 CADH1_MOUSE (1-916): 0: 695: 42.27		CTNA1_MOUSE (7-891): 0: 986: 59.28
+	Hs
		716678 DSG2_HUMAN (149-735): 1.22e-87: 305: 32.50		CTNA1_HUMAN (7-891): 0: 992: 59.40
+	Hs
		877559 CAD12_HUMAN (7-498): 2.56e-72: 256: 18.41		CTNA3_HUMAN (1-895): 0: 1016: 100.00
+	Hs
		640714 CAD12_HUMAN (7-498): 2.56e-72: 256: 18.41		CTNA2_HUMAN (2-891): 0: 1002: 57.66
+	Hs
		716641 CAD12_HUMAN (7-498): 2.56e-72: 256: 18.41		CTNA1_HUMAN (7-891): 0: 992: 59.40
+	Hs
		606311 CADH3_HUMAN (4-595): 2.13e-57: 214: 20.06		CTNA3_HUMAN (1-895): 0: 1016: 100.00
+	Hs
		606300 CADH3_HUMAN (4-595): 2.13e-57: 214: 20.06		CTNA1_HUMAN (7-891): 0: 992: 59.40
+	Hs
		1355726 CAD10_HUMAN (16-382): 4.44e-48: 185: 17.98		CTNA3_HUMAN (1-895): 0: 1016: 100.00
+	Hs
		640703 CADH5_HUMAN (33-531): 1.45e-49: 190: 20.23		CTNA2_HUMAN (2-891): 0: 1002: 57.66
+	Hs
		702744 CADH5_HUMAN (33-531): 1.45e-49: 190: 20.23		CTNA1_HUMAN (7-891): 0: 992: 59.40
+	Hs
		640713 CADH8_HUMAN (16-382): 6e-45: 176: 19.14		CTNA2_HUMAN (2-891): 0: 1002: 57.66
+	Hs
		716640 CADH8_HUMAN (16-382): 6e-45: 176: 19.14		CTNA1_HUMAN (7-891): 0: 992: 59.40
+	Hs
		1199809 CAD24_HUMAN (16-382): 2.64e-34: 143: 17.32		CTNA3_HUMAN (1-895): 0: 1016: 100.00
+	Hs
		716725 CAD24_HUMAN (16-382): 2.64e-34: 143: 17.32		CTNA1_HUMAN (7-891): 0: 992: 59.40
+	Mm
		640688 CADH5_MOUSE (33-386): 3.75e-36: 148: 19.56		CTNA1_MOUSE (7-891): 0: 986: 59.28
+	Hs
		521714 CADH1_HUMAN (26-916): 0: 728: 42.59		VINC_HUMAN (20-615): 2.01e-62: 231: 15.93
+	Hs
		575694 CADH5_HUMAN (33-531): 1.45e-49: 190: 20.23		VINC_HUMAN (20-615): 2.01e-62: 231: 15.93