HitPredict

Interactor 1: LHX4 (P53776)
LIM/homeobox protein Lhx4 (LIM homeobox protein 4)
Gene: LHX4

Interactor 2: LDB1 (P70662)
LIM domain-binding protein 1 (LDB-1) (Carboxyl-terminal LIM domain-binding protein 2) (CLIM-2) (LIM domain-binding factor CLIM2) (mLdb1) (Nuclear LIM interactor)
Gene: LDB1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	20211142
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	LID~LIM
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 390 Mm			1 411
+	Hs
		1287917 LHX4_HUMAN (1-390): 6.42e-114: 339: 98.97		LDB1_HUMAN (1-411): 0: 760: 99.76
+	Hs
		1287935 LHX3_HUMAN (24-390): 2.55e-95: 292: 64.00		LDB1_HUMAN (1-411): 0: 760: 99.76
+	Mm
		895873 LHX3_MOUSE (7-390): 1.34e-88: 274: 61.22		LDB1_MOUSE (1-411): 0: 760: 100.00
+	Hs
		877527 LHX1_HUMAN (29-389): 1.92e-67: 220: 31.40		LDB1_HUMAN (1-411): 0: 760: 99.76
+	Mm
		988942 LHX1_MOUSE (29-389): 1.41e-67: 220: 31.40		LDB1_MOUSE (1-411): 0: 760: 100.00
+	Mm
		961503 LHX5_MOUSE (29-388): 8.8e-66: 216: 32.27		LDB1_MOUSE (1-411): 0: 760: 100.00
+	Mm
		1000518 LMX1A_MOUSE (2-343): 1.81e-64: 212: 27.39		LDB1_MOUSE (1-411): 0: 760: 100.00
+	Mm
		237320 LHX4_MOUSE (1-390): 3.89e-114: 340: 100.00		LDB2_MOUSE (44-411): 0: 626: 76.15
+	Hs
		253019 LMX1B_HUMAN (10-314): 2.82e-61: 204: 29.10		LDB1_HUMAN (1-411): 0: 760: 99.76
+	Mm
		312694 LMX1B_MOUSE (10-314): 7.29e-61: 203: 29.40		LDB1_MOUSE (1-411): 0: 760: 100.00
+	Hs
		223938 LHX4_HUMAN (1-390): 6.42e-114: 339: 98.97		LDB2_HUMAN (44-411): 0: 620: 76.42
+	Hs
		223951 LHX3_HUMAN (24-390): 2.55e-95: 292: 64.00		LDB2_HUMAN (44-411): 0: 620: 76.42
+	Mm
		237324 LHX1_MOUSE (29-389): 1.41e-67: 220: 31.40		LDB2_MOUSE (44-411): 0: 626: 76.15
+	Mm
		237322 LHX5_MOUSE (29-388): 8.8e-66: 216: 32.27		LDB2_MOUSE (44-411): 0: 626: 76.15
+	Mm
		237334 LMX1A_MOUSE (2-343): 1.81e-64: 212: 27.39		LDB2_MOUSE (44-411): 0: 626: 76.15
+	Dm
		120438 M9PD53_DROME (6-386): 8.1e-74: 241: 46.92		O18353_DROME (8-391): 0: 594: 56.89
+	Dm
		197475 Q9VJ00_DROME (6-386): 1.7e-73: 239: 46.92		O18353_DROME (8-391): 0: 594: 56.89
+	Dm
		118250 M9NCY1_DROME (26-386): 9.11e-74: 237: 48.65		Q7KVG9_DROME (8-391): 0: 593: 56.89
+	Mm
		237317 LMX1B_MOUSE (10-314): 7.29e-61: 203: 29.40		LDB2_MOUSE (44-411): 0: 626: 76.15
+	Ce
		112577 HM14_CAEEL (20-336): 8.89e-62: 204: 41.30		LIDB1_CAEEL (33-408): 2.6e-137: 407: 27.85