Protein: O18353
CHIP (LD25129p)

Gene: O18353, Chi
Organism: Drosophila melanogaster
Interactions: 74
UniProt ID: O18353

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0005667 - transcription regulator complex
GO:0007350 - blastoderm segmentation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

197468

Q9V472
DLim1

2

20

High-throughput

0.754

High

197477

Q9VL21
LD11652p

2

20

High-throughput

0.754

High

197485

Q9VTW3
FI06571p

2

20

High-throughput

0.754

High

197486

Q9VTW5
LIM homeobox transcription factor 1 alpha, isoform B

2

20

High-throughput

0.754

High

197453

Q8IQX7
Beadex, isoform B

2

20

High-throughput

0.745

High

197440

APTE
Protein apterous

2

20

High-throughput

0.689

High

120438

M9PD53
Lim3, isoform G

1

20

High-throughput

0.637

High

197454

AWH
LIM/homeobox protein Awh

1

20

High-throughput

0.637

High

197503

Q9Y0Z9
Insulin gene enhancer protein ISL-1

1

20

High-throughput

0.637

High

197475

Q9VJ00
FI01025p

1

20

High-throughput

0.590

High

197476

Q9VJ37
Insulin gene enhancer protein ISL-1

1

20

High-throughput

0.590

High

197499

Q9W279
FI01029p

2

1

High-throughput

0.584

High

197470

Q9VEB9
Sequence-specific single-stranded DNA-binding protein, isoform A

2

13

High-throughput

0.562

High

197447

Q7K3Z3
GH01724p

1

1

High-throughput

0.457

High

197450

LOLA4
Longitudinals lacking protein, isoforms F/I/K/T

1

2

High-throughput

0.457

High

197487

Q9VTW6
U6 snRNA-associated Sm-like protein LSm2

1

1

High-throughput

0.457

High

197452

OSA
Trithorax group protein osa

1

1

High-throughput

0.445

High

197463

Q95TT5
LD24616p

1

1

High-throughput

0.445

High

197483

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

1

High-throughput

0.445

High

197491

MED12
Mediator of RNA polymerase II transcription subunit 12

1

1

High-throughput

0.445

High

197493

BAP60
Brahma-associated protein of 60 kDa

1

1

High-throughput

0.445

High

197496

MED14
Mediator of RNA polymerase II transcription subunit 14

1

1

High-throughput

0.445

High

197500

Q9W3G1
Uncharacterized protein, isoform A

1

1

High-throughput

0.445

High

197504

MED15
Mediator of RNA polymerase II transcription subunit 15

1

1

High-throughput

0.445

High

58458

MED8
Mediator of RNA polymerase II transcription subunit 8

1

0

High-throughput

0.426

High

197439

BRM
ATP-dependent helicase brm

1

0

High-throughput

0.426

High

197441

DSH
Segment polarity protein dishevelled

1

0

High-throughput

0.426

High

197443

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.426

High

197444

Q24090
GH08712p

1

0

High-throughput

0.426

High

197445

Q7JQT8
LD41464p

1

0

High-throughput

0.426

High

197448

MED29
Mediator of RNA polymerase II transcription subunit 29

1

0

High-throughput

0.426

High

197449

MED13
Mediator of RNA polymerase II transcription subunit 13

1

0

High-throughput

0.426

High

197451

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.426

High

197458

MED6
Mediator of RNA polymerase II transcription subunit 6

1

0

High-throughput

0.426

High

197460

ENA
Protein enabled

1

0

High-throughput

0.426

High

197462

EBI
F-box-like/WD repeat-containing protein ebi

1

0

High-throughput

0.426

High

197465

Q9BIW6
Brahma-associated protein 111kD

1

0

High-throughput

0.426

High

197466

MED10
Mediator of RNA polymerase II transcription subunit 10

1

0

High-throughput

0.426

High

197467

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

High-throughput

0.426

High

197469

MED25
Mediator of RNA polymerase II transcription subunit 25

1

0

High-throughput

0.426

High

197471

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.426

High

197472

Q9VF03
Brahma associated protein 155 kDa

1

0

High-throughput

0.426

High

197478

Q9VL29
GEO11246p1

1

0

High-throughput

0.426

High

197479

MED27
Mediator of RNA polymerase II transcription subunit 27

1

0

High-throughput

0.426

High

197481

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.426

High

197482

MED24
Mediator of RNA polymerase II transcription subunit 24

1

0

High-throughput

0.426

High

197484

CDK8
Cyclin-dependent kinase 8

1

0

High-throughput

0.426

High

197489

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.426

High

197490

MED11
Mediator of RNA polymerase II transcription subunit 11

1

0

High-throughput

0.426

High

197495

MED30
Mediator of RNA polymerase II transcription subunit 30

1

0

High-throughput

0.426

High

197497

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.426

High

197498

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.426

High

197502

MED18
Mediator of RNA polymerase II transcription subunit 18

1

0

High-throughput

0.426

High

195216

O16158
Calcium-binding protein

1

1

High-throughput

0.417

High

197435

LCP2
Larval cuticle protein 2

1

1

High-throughput

0.417

High

197446

Q7K049
AT10229p

1

3

High-throughput

0.417

High

197455

Q8IRZ1
Uncharacterized protein, isoform B

1

4

High-throughput

0.417

High

197456

Q8MRL0
GH25858p

1

1

High-throughput

0.417

High

197459

Q8T3Z0
Tektin

1

4

High-throughput

0.417

High

197473

Q9VGV7
CG4570 protein

1

1

High-throughput

0.417

High

197474

Q9VI39
AT17667p

1

1

High-throughput

0.417

High

197480

Q9VPH6
LP10922p

1

1

High-throughput

0.417

High

197492

Q9VY48
Large ribosomal subunit protein mL38

1

1

High-throughput

0.417

High

197501

Q9W4L6
GEO10192p1

1

1

High-throughput

0.417

High

197434

FTZ
Segmentation protein fushi tarazu

1

9

High-throughput

0.381

High

197436

SUHW
Zinc finger protein su(Hw)

1

1

High-throughput

0.381

High

197437

BCD
Homeotic protein bicoid

1

12

High-throughput

0.381

High

197438

HMOC
Homeotic protein ocelliless

1

20

High-throughput

0.381

High

197442

PNR
GATA-binding factor A

1

3

High-throughput

0.381

High

197457

ENC
Protein encore

1

0

High-throughput

0.232

Low

197461

MESD
LDLR chaperone boca

1

0

High-throughput

0.232

Low

197464

Q960F7
SD03629p

1

0

High-throughput

0.232

Low

197488

Q9VUB7
PAX-interacting protein 1

1

0

High-throughput

0.232

Low

197494

Q9W0L7
ubiquitinyl hydrolase 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025