Interactor 1: UB2R1 (P49427)
Ubiquitin-conjugating enzyme E2 R1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme R1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme R1) (Ubiquitin-conjugating enzyme E2-32 kDa complementing) (Ubiquitin-conjugating enzyme E2-CDC34) (Ubiquitin-protein ligase R1)
Gene: CDC34

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 19256485
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin_Nedd8~UQ_con
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000209 - protein polyubiquitination
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 236
Hs

1 768
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Service provided by Combinatics, Japan

Last updated: 11Aug2025