HitPredict

Interactor 1: ACTN (P18091)
Alpha-actinin, sarcomeric (F-actin cross-linking protein)
Gene: ACTN

Interactor 2: Q95TZ7 (Q95TZ7)
GH19182p (Z band alternatively spliced PDZ-motif protein 66, isoform F)
Gene: Zasp66

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	23505387, 14605208
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0030018 - Z disc GO:0030036 - actin cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 924 Dm			1 402
+	Dm
		574818 ACTN_DROME (1-924): 0: 652: 100.00		Q8IQB4_DROME (14-402): 1.96e-92: 286: 93.06
+	Mm
		1186636 ACTN1_MOUSE (5-924): 0: 643: 67.39		PDLI5_MOUSE (5-372): 3.48e-50: 179: 16.75
+	Hs
		254383 ACTN1_HUMAN (5-924): 0: 646: 67.61		LDB3_HUMAN (7-277): 2.96e-45: 168: 19.85
+	Hs
		521529 ACTN1_HUMAN (5-924): 0: 646: 67.61		ZO1_HUMAN (2-383): 3.59e-41: 157: 14.57
+	Hs
		117245 ACTN1_HUMAN (5-924): 0: 646: 67.61		PDLI1_HUMAN (8-253): 1.11e-38: 143: 17.00
+	Hs
		521623 ACTN1_HUMAN (5-924): 0: 646: 67.61		PDLI7_HUMAN (5-232): 1.54e-36: 140: 19.39
+	Rn
		1149817 ACTN1_RAT (5-924): 0: 648: 67.61		PDLI2_RAT (9-265): 3.29e-36: 137: 21.37
+	Hs
		521502 ACTN1_HUMAN (5-924): 0: 646: 67.61		PDLI4_HUMAN (13-246): 2.64e-35: 134: 23.01
+	Dm
		54833 ACTN_DROME (1-924): 0: 652: 100.00		ZASP_DROME (18-124): 4.73e-27: 115: 33.03
+	Hs
		521616 ACTN1_HUMAN (5-924): 0: 646: 67.61		SYP2L_HUMAN (5-248): 7.92e-28: 118: 18.51
+	Hs
		211570 ACTN4_HUMAN (14-924): 0: 598: 67.40		ZO1_HUMAN (2-383): 3.59e-41: 157: 14.57
+	Hs
		117270 ACTN3_HUMAN (21-924): 0: 605: 66.04		PDLI1_HUMAN (8-253): 1.11e-38: 143: 17.00
+	Mm
		1337461 ACTN2_MOUSE (5-924): 0: 597: 66.52		LDB3_MOUSE (7-277): 1.41e-38: 149: 19.05
+	Hs
		117234 ACTN4_HUMAN (14-924): 0: 598: 67.40		PDLI1_HUMAN (8-253): 1.11e-38: 143: 17.00
+	Hs
		211672 ACTN4_HUMAN (14-924): 0: 598: 67.40		PDLI7_HUMAN (5-232): 1.54e-36: 140: 19.39
+	Rn
		1149816 ACTN4_RAT (14-924): 0: 595: 67.51		PDLI2_RAT (9-265): 3.29e-36: 137: 21.37
+	Hs
		993296 ACTN3_HUMAN (21-924): 0: 605: 66.04		SYP2L_HUMAN (5-248): 7.92e-28: 118: 18.51
+	Hs
		521598 ACTN1_HUMAN (5-924): 0: 646: 67.61		MAGI1_HUMAN (14-361): 3.83e-13: 73.6: 11.17
+	Hs
		211645 ACTN4_HUMAN (14-924): 0: 598: 67.40		MAGI1_HUMAN (14-361): 3.83e-13: 73.6: 11.17
+	Mm
		1267826 ACTN2_MOUSE (5-924): 0: 597: 66.52		GRIP1_MOUSE (7-101): 4.35e-11: 67: 21.65