HitPredict

Interactor 1: SOX8 (P57073)
Transcription factor SOX-8
Gene: SOX8

Interactor 2: PF21A (Q96BD5)
PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80)
Gene: PHF21A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34709266
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003677 - DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 446 Hs			1 680
+	Hs
		1285342 SOX7_HUMAN (87-389): 1.1e-41: 154: 26.56		PF21A_HUMAN (1-680): 2.54e-112: 355: 100.00
+	Hs
		1285335 CIC_HUMAN (24-318): 1.09e-31: 131: 17.55		PF21A_HUMAN (1-680): 2.54e-112: 355: 100.00
+	Hs
		1285365 HM20A_HUMAN (9-225): 2.6e-33: 130: 11.69		PF21A_HUMAN (1-680): 2.54e-112: 355: 100.00
+	Hs
		1311941 SOX7_HUMAN (87-389): 1.1e-41: 154: 26.56		TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08
+	Hs
		1332331 SOX17_HUMAN (99-353): 2.68e-41: 153: 30.74		TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08
+	Hs
		170464 SOX7_HUMAN (87-389): 1.1e-41: 154: 26.56		TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56
+	Hs
		170476 SOX17_HUMAN (99-353): 2.68e-41: 153: 30.74		TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56
+	Hs
		170279 SOX5_HUMAN (18-178): 3.3e-34: 137: 26.71		TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56
+	Hs
		170345 SSRP1_HUMAN (19-262): 2.89e-30: 125: 15.98		TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56
+	Hs
		1300981 CIC_HUMAN (24-318): 1.09e-31: 131: 17.55		BAZ2A_HUMAN (4-648): 1.81e-50: 192: 11.71
+	Hs
		727856 SOX6_HUMAN (15-298): 1.98e-38: 150: 20.39		CHD3_HUMAN (298-617): 4.98e-41: 163: 15.21
+	Hs
		1059891 TF7L2_HUMAN (13-345): 2.06e-34: 137: 13.77		CHD4_HUMAN (324-650): 1.2e-41: 165: 16.04
+	Hs
		727736 SOX5_HUMAN (18-178): 3.3e-34: 137: 26.71		CHD3_HUMAN (298-617): 4.98e-41: 163: 15.21
+	Hs
		225761 SOX15_HUMAN (102-234): 9.86e-34: 128: 43.92		CHD5_HUMAN (255-617): 2.01e-43: 170: 16.79
+	Hs
		1059807 CIC_HUMAN (24-318): 1.09e-31: 131: 17.55		CHD4_HUMAN (324-650): 1.2e-41: 165: 16.04
+	Hs
		996673 SSRP1_HUMAN (19-262): 2.89e-30: 125: 15.98		CHD4_HUMAN (324-650): 1.2e-41: 165: 16.04
+	Hs
		996636 SSRP1_HUMAN (19-262): 2.89e-30: 125: 15.98		CHD3_HUMAN (298-617): 4.98e-41: 163: 15.21
+	Hs
		996848 SSRP1_HUMAN (19-262): 2.89e-30: 125: 15.98		RSF1_HUMAN (156-578): 3.04e-34: 142: 16.59
+	Hs
		217472 SSRP1_HUMAN (19-262): 2.89e-30: 125: 15.98		AIRE_HUMAN (472-538): 1.24e-19: 94.9: 43.06
+	Hs
		1300602 CIC_HUMAN (24-318): 1.09e-31: 131: 17.55		PHF12_HUMAN (462-541): 1.99e-13: 76: 31.71