HitPredict

Interactor 1: SYJ2B (P57105)
Synaptojanin-2-binding protein (Mitochondrial outer membrane protein 25)
Gene: SYNJ2BP

Interactor 2: LRP2 (P98164)
Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)
Gene: LRP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.50	0.481

Property	Details
Experiments	10827173
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 145 Hs			1 4655
+	Hs
		942324 DLG4_HUMAN (3-142): 4.24e-27: 106: 31.94		LRP2_HUMAN (1-4655): 0: 3803: 100.00
+	Hs
		957608 DLG2_HUMAN (6-142): 7.86e-27: 106: 29.79		LRP2_HUMAN (1-4655): 0: 3803: 100.00
+	Hs
		957631 DLG3_HUMAN (1-121): 2.05e-23: 96.6: 38.84		LRP2_HUMAN (1-4655): 0: 3803: 100.00
+	Mm
		57561 SYJ2B_MOUSE (1-145): 6.21e-45: 145: 91.03		LRP2_MOUSE (22-4655): 0: 3723: 76.66
+	Mm
		57555 DLG4_MOUSE (3-142): 4.36e-27: 106: 31.94		LRP2_MOUSE (22-4655): 0: 3723: 76.66
+	Hs
		883911 SYJ2B_HUMAN (1-145): 1.52e-45: 147: 100.00		LRP8_HUMAN (3464-3669): 8.96e-14: 80.7: 21.92
+	Hs
		883908 SYJ2B_HUMAN (1-145): 1.52e-45: 147: 100.00		LRP1_HUMAN (1102-1387): 4.45e-09: 65.6: 13.59
+	Mm
		1265297 SYJ2B_MOUSE (1-145): 6.21e-45: 145: 91.03		LRP1_MOUSE (3672-3974): 3.08e-09: 66: 10.16
+	Dm
		113371 M9NFI9_DROME (14-110): 8.14e-30: 115: 32.65		Q9VBN2_DROME (3826-4054): 4.69e-13: 78.3: 25.97
+	Dm
		113267 M9NFI9_DROME (14-110): 8.14e-30: 115: 32.65		Q8IRV8_DROME (25-99): 2.91e-11: 72.8: 41.77
+	Dm
		113773 M9NFI9_DROME (14-110): 8.14e-30: 115: 32.65		Q9W4Y3_DROME (25-99): 5.33e-11: 72: 41.77
+	Hs
		942339 DLG4_HUMAN (3-142): 4.24e-27: 106: 31.94		LRP8_HUMAN (3464-3669): 8.96e-14: 80.7: 21.92
+	Mm
		1267815 SNTG2_MOUSE (3-144): 2.89e-31: 118: 23.38		LRP1B_MOUSE (3573-3844): 8.78e-09: 64.5: 13.41
+	Mm
		1143476 DLG4_MOUSE (3-142): 4.36e-27: 106: 31.94		LRP8_MOUSE (2623-2869): 2.33e-11: 72.6: 16.36
+	Mm
		69882 DLG4_MOUSE (3-142): 4.36e-27: 106: 31.94		B1AXJ3_MOUSE (3424-3628): 4.43e-11: 71.8: 12.50
+	Mm
		57225 A2AKD7_MOUSE (7-141): 5.86e-28: 108: 25.00		NID1_MOUSE (2773-2970): 3.23e-09: 65.6: 13.86
+	Mm
		1143471 DLG4_MOUSE (3-142): 4.36e-27: 106: 31.94		LRP1_MOUSE (3672-3974): 3.08e-09: 66: 10.16
+	Hs
		942331 DLG4_HUMAN (3-142): 4.24e-27: 106: 31.94		LRP1_HUMAN (1102-1387): 4.45e-09: 65.6: 13.59