HitPredict

Interactor 1: H2B1D (P58876)
Histone H2B type 1-D (H2B-clustered histone 5) (HIRA-interacting protein 2) (Histone H2B.1 B) (Histone H2B.b) (H2B/b)
Gene: H2BC5

Interactor 2: IGSF8 (Q969P0)
Immunoglobulin superfamily member 8 (IgSF8) (CD81 partner 3) (Glu-Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes-associated transmembrane protein 4) (KCT-4) (LIR-D1) (Prostaglandin regulatory-like protein) (PGRL) (CD antigen CD316)
Gene: IGSF8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23463506
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~V-set
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 613
+	Hs
		1129835 H2B2F_HUMAN (1-126): 3.9e-54: 167: 97.62		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		1281777 H2B1M_HUMAN (1-126): 4.45e-54: 167: 96.83		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		1274395 H2B1H_HUMAN (1-126): 8.88e-54: 166: 98.41		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		420868 H2B1J_HUMAN (1-126): 1.25e-53: 166: 97.62		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		617967 H2B1O_HUMAN (1-126): 5.42e-54: 166: 97.62		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		241603 H2B1K_HUMAN (1-126): 2.11e-53: 165: 98.41		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		707706 H2B1B_HUMAN (1-126): 1.77e-53: 165: 97.62		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		918584 H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21		IGSF8_HUMAN (1-613): 5.61e-173: 507: 100.00
+	Hs
		253656 H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41		IGSF3_HUMAN (19-305): 3.84e-20: 97.2: 17.89
+	Hs
		253633 H2B1D_HUMAN (1-126): 2.74e-53: 165: 100.00		IGSF3_HUMAN (19-305): 3.84e-20: 97.2: 17.89
+	Hs
		1129830 H2B2F_HUMAN (1-126): 3.9e-54: 167: 97.62		TITIN_HUMAN (169-612): 1.96e-12: 72.9: 9.60
+	Hs
		1087299 H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41		TITIN_HUMAN (169-612): 1.96e-12: 72.9: 9.60
+	Hs
		1264778 H2B1H_HUMAN (1-126): 8.88e-54: 166: 98.41		TITIN_HUMAN (169-612): 1.96e-12: 72.9: 9.60
+	Hs
		617962 H2B1O_HUMAN (1-126): 5.42e-54: 166: 97.62		TITIN_HUMAN (169-612): 1.96e-12: 72.9: 9.60
+	Hs
		241595 H2B1K_HUMAN (1-126): 2.11e-53: 165: 98.41		TITIN_HUMAN (169-612): 1.96e-12: 72.9: 9.60
+	Hs
		883041 H2BFS_HUMAN (1-126): 1.64e-53: 165: 96.83		TITIN_HUMAN (169-612): 1.96e-12: 72.9: 9.60
+	Hs
		886166 H2B1D_HUMAN (1-126): 2.74e-53: 165: 100.00		TITIN_HUMAN (169-612): 1.96e-12: 72.9: 9.60
+	Hs
		918561 H2B1C_HUMAN (1-126): 1.71e-53: 165: 99.21		TITIN_HUMAN (169-612): 1.96e-12: 72.9: 9.60
+	Hs
		1087182 H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41		OBSCN_HUMAN (104-544): 1.7e-11: 69.7: 14.13
+	Hs
		255826 H2B2E_HUMAN (1-126): 9.91e-54: 166: 98.41		OBSL1_HUMAN (92-559): 2.57e-11: 69.3: 15.13