HitPredict

Interactor 1: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Interactor 2: IQG1 (Q12280)
Ras GTPase-activating-like protein IQG1 (Cytokinesis protein 1) (IQGAP-related protein 1)
Gene: IQG1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	1.00	0.806

Property	Details
Experiments	9950677, 9679143
Identification Methods	cosedimentation in solution, experimental interaction detection, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Actin~CH
Common GO terms	GO:0000142 - cellular bud neck contractile ring
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 375 Sc			1 1495
+	Hs
		891748 ACTB_HUMAN (1-375): 0: 601: 88.80		IQGA2_HUMAN (88-1492): 0: 853: 15.36
+	Sp
		144980 ACT_SCHPO (1-375): 0: 591: 89.60		IQG1_SCHPO (90-1490): 0: 791: 20.38
+	Hs
		548718 ACTBL_HUMAN (2-375): 0: 687: 83.42		VAV_HUMAN (117-568): 6.07e-72: 261: 12.62
+	Hs
		1122483 ACTBL_HUMAN (2-375): 0: 687: 83.42		SYGP1_HUMAN (827-1224): 5.68e-68: 254: 12.26
+	Hs
		596386 ACTB_HUMAN (1-375): 0: 601: 88.80		RASA1_HUMAN (741-1168): 1.07e-68: 254: 8.84
+	Hs
		891983 ACTB_HUMAN (1-375): 0: 601: 88.80		SYGP1_HUMAN (827-1224): 5.68e-68: 254: 12.26
+	Hs
		596392 ACTG_HUMAN (1-375): 0: 600: 89.07		RASA1_HUMAN (741-1168): 1.07e-68: 254: 8.84
+	Hs
		929973 ACTG_HUMAN (1-375): 0: 600: 89.07		SYGP1_HUMAN (827-1224): 5.68e-68: 254: 12.26
+	Hs
		932163 ACTC_HUMAN (2-375): 0: 591: 87.17		GAPD1_HUMAN (751-1282): 6.49e-68: 255: 11.73
+	Hs
		892114 ACTB_HUMAN (1-375): 0: 601: 88.80		LIMC1_HUMAN (112-458): 1.17e-60: 230: 18.21
+	Hs
		891782 ACTB_HUMAN (1-375): 0: 601: 88.80		CNN3_HUMAN (90-366): 7.13e-64: 222: 15.04
+	Hs
		932175 ACTC_HUMAN (2-375): 0: 591: 87.17		CNN3_HUMAN (90-366): 7.13e-64: 222: 15.04
+	Hs
		809232 ACTB_HUMAN (1-375): 0: 601: 88.80		IQGA1_HUMAN (88-1320): 2.1e-49: 195: 12.22
+	Hs
		809257 ACTG_HUMAN (1-375): 0: 600: 89.07		IQGA1_HUMAN (88-1320): 2.1e-49: 195: 12.22
+	Hs
		891988 ACTB_HUMAN (1-375): 0: 601: 88.80		CNN2_HUMAN (78-366): 1.65e-50: 183: 12.80
+	Dm
		862565 ACT3_DROME (2-375): 0: 593: 87.97		Q9I7J0_DROME (112-244): 4.99e-41: 151: 32.35
+	Hs
		741850 ACTB_HUMAN (1-375): 0: 601: 88.80		TAGL2_HUMAN (106-243): 3.48e-13: 71.8: 17.57
+	Hs
		741855 ACTG_HUMAN (1-375): 0: 600: 89.07		TAGL2_HUMAN (106-243): 3.48e-13: 71.8: 17.57
+	Sc
		887705 ACT_YEAST (1-375): 0: 594: 100.00		SCP1_YEAST (111-230): 4.76e-15: 77.2: 27.42
+	Hs
		741856 ACTC_HUMAN (2-375): 0: 591: 87.17		TAGL2_HUMAN (106-243): 3.48e-13: 71.8: 17.57