HitPredict

Interactor 1: RGS3 (P49796)
Regulator of G-protein signaling 3 (RGP3) (RGS3)
Gene: RGS3

Interactor 2: SEPT8 (Q92599)
Septin-8
Gene: SEPTIN8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1198 Hs			1 483
+	Hs
		890690 RGS3_HUMAN (1-1198): 0: 953: 100.00		SEP10_HUMAN (1-429): 0: 586: 72.96
+	Hs
		890649 RGS3_HUMAN (1-1198): 0: 953: 100.00		SEPT6_HUMAN (1-429): 0: 580: 76.22
+	Hs
		890657 RGS3_HUMAN (1-1198): 0: 953: 100.00		SEPT7_HUMAN (2-427): 0: 547: 40.83
+	Hs
		890686 RGS3_HUMAN (1-1198): 0: 953: 100.00		SEP11_HUMAN (11-402): 0: 546: 81.12
+	Hs
		890653 RGS3_HUMAN (1-1198): 0: 953: 100.00		SEPT2_HUMAN (9-353): 1.01e-162: 466: 38.98
+	Hs
		890695 RGS3_HUMAN (1-1198): 0: 953: 100.00		SEPT9_HUMAN (8-319): 8.09e-157: 459: 39.81
+	Hs
		890694 RGS3_HUMAN (1-1198): 0: 953: 100.00		SEPT3_HUMAN (9-309): 1.89e-155: 447: 42.40
+	Hs
		603267 KPCA_HUMAN (124-271): 6.1e-71: 253: 30.87		SEPT6_HUMAN (1-429): 0: 580: 76.22
+	Hs
		603382 KPCA_HUMAN (124-271): 6.1e-71: 253: 30.87		SEPT9_HUMAN (8-319): 8.09e-157: 459: 39.81