HitPredict

Interactor 1: ACTB (P60710)
Actin, cytoplasmic 1 (Beta-actin) (EC 3.6.4.-) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: MILK2 (Q3TN34)
MICAL-like protein 2 (Junctional Rab13-binding protein) (Molecule interacting with CasL-like 2) (MICAL-L2)
Gene: Micall2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	18332111
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Actin~CH
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 375 Mm			1 1009
+	Hs
		891887 ACTB_HUMAN (1-375): 0: 603: 100.00		MILK2_HUMAN (1-743): 2.37e-75: 268: 41.29
+	Hs
		725637 ACTB_HUMAN (1-375): 0: 603: 100.00		ACTN2_HUMAN (2-226): 1.64e-66: 243: 27.11
+	Hs
		211548 ACTB_HUMAN (1-375): 0: 603: 100.00		ACTN4_HUMAN (2-222): 2.11e-65: 239: 26.70
+	Hs
		506816 ACTB_HUMAN (1-375): 0: 603: 100.00		SPTB1_HUMAN (2-218): 6.51e-63: 236: 29.03
+	Hs
		891697 ACTB_HUMAN (1-375): 0: 603: 100.00		SPTB2_HUMAN (2-214): 8.89e-61: 229: 29.11
+	Hs
		211560 ACTC_HUMAN (2-375): 0: 592: 94.12		ACTN4_HUMAN (2-222): 2.11e-65: 239: 26.70
+	Hs
		211561 ACTS_HUMAN (2-375): 0: 592: 93.58		ACTN4_HUMAN (2-222): 2.11e-65: 239: 26.70
+	Hs
		929824 ACTG_HUMAN (1-375): 0: 601: 98.93		SPTB2_HUMAN (2-214): 8.89e-61: 229: 29.11
+	Hs
		932107 ACTC_HUMAN (2-375): 0: 592: 94.12		SPTB2_HUMAN (2-214): 8.89e-61: 229: 29.11
+	Hs
		164588 ACTB_HUMAN (1-375): 0: 603: 100.00		SPTN2_HUMAN (2-214): 1.35e-56: 216: 28.64
+	Dm
		361167 ACT4_DROME (2-375): 0: 589: 94.65		ACTN_DROME (1-226): 1.23e-61: 229: 23.32
+	Oc
		933099 ACTS_RABIT (2-375): 0: 592: 93.58		Q07931_RABIT (2-132): 1.19e-59: 208: 41.22
+	Sp
		142705 ACT_SCHPO (1-375): 0: 592: 90.40		AIN1_SCHPO (1-215): 4.28e-54: 201: 24.07