HitPredict

Interactor 1: MEOX2 (P50222)
Homeobox protein MOX-2 (Growth arrest-specific homeobox) (Mesenchyme homeobox 2)
Gene: MEOX2

Interactor 2: HMBX1 (Q6NT76)
Homeobox-containing protein 1 (Homeobox telomere-binding protein 1) (Telomere-associated homeobox-containing protein 1)
Gene: HMBOX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Homeodomain~Homeodomain
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0043565 - sequence-specific DNA binding GO:1990837 - sequence-specific double-stranded DNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 304 Hs			1 420
+	Hs
		1232410 Q6FHY5_HUMAN (1-304): 9.73e-57: 187: 98.36		HMBX1_HUMAN (1-420): 9.33e-128: 377: 100.00
+	Hs
		662310 MEOX2_HUMAN (1-304): 2.02e-58: 191: 100.00		PAX3_HUMAN (75-410): 1.46e-74: 242: 17.92
+	Mm
		666046 MEOX2_MOUSE (1-304): 1.85e-55: 183: 96.71		PAX3_MOUSE (75-410): 3.84e-75: 243: 17.92
+	Mm
		666045 MEOX1_MOUSE (4-270): 1.17e-33: 125: 36.26		PAX3_MOUSE (75-410): 3.84e-75: 243: 17.92
+	Ce
		111895 MEC3_CAEEL (31-264): 1.39e-32: 124: 20.23		VAB3_CAEEL (70-418): 2.64e-67: 222: 15.04
+	Hs
		586394 MEOX2_HUMAN (1-304): 2.02e-58: 191: 100.00		PAX1_HUMAN (45-265): 1.83e-35: 139: 13.66
+	Ce
		479010 MEC3_CAEEL (31-264): 1.39e-32: 124: 20.23		HMBX1_CAEEL (22-415): 1.84e-59: 201: 24.25
+	Dm
		478865 UBX_DROME (37-248): 1.06e-29: 118: 21.23		GSBN_DROME (56-381): 1.38e-59: 202: 15.16
+	Mm
		478870 MEOX2_MOUSE (1-304): 1.85e-55: 183: 96.71		PAX1_MOUSE (45-265): 5.09e-35: 136: 12.78
+	Ce
		111459 MEC3_CAEEL (31-264): 1.39e-32: 124: 20.23		PAX3H_CAEEL (75-376): 1.43e-52: 179: 13.92
+	Mm
		648022 EMX1_MOUSE (69-260): 3.27e-32: 121: 27.64		HNF1A_MOUSE (21-416): 3.42e-48: 175: 18.36
+	Hs
		478663 HXB5_HUMAN (108-262): 1.48e-35: 130: 32.75		NKX21_HUMAN (115-382): 7.66e-35: 134: 11.36
+	Mm
		478869 MEOX1_MOUSE (4-270): 1.17e-33: 125: 36.26		PAX1_MOUSE (45-265): 5.09e-35: 136: 12.78
+	Hs
		700820 PIT1_HUMAN (1-252): 3.08e-37: 135: 15.81		PITX1_HUMAN (237-389): 3.75e-32: 125: 24.84
+	Ce
		117753 MEC3_CAEEL (31-264): 1.39e-32: 124: 20.23		UNC42_CAEEL (203-419): 2.04e-32: 125: 14.75
+	Hs
		184760 SHOX_HUMAN (166-249): 2.27e-31: 120: 34.52		SHOX_HUMAN (183-375): 1.04e-32: 126: 18.27
+	Dm
		662105 UBX_DROME (37-248): 1.06e-29: 118: 21.23		POXM_DROME (73-255): 7.42e-31: 123: 16.23
+	Dm
		1014305 UBX_DROME (37-248): 1.06e-29: 118: 21.23		AL_DROME (233-376): 3.02e-30: 122: 21.53
+	Dm
		1014417 UBX_DROME (37-248): 1.06e-29: 118: 21.23		Q9W1H7_DROME (256-354): 4.33e-30: 117: 23.23
+	Dm
		1014427 UBX_DROME (37-248): 1.06e-29: 118: 21.23		Q9XZU0_DROME (264-340): 5.16e-14: 74.7: 27.27