HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: M3K11 (Q16584)
Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)
Gene: MAP3K11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.677

The method score is based on:

Property Details
Experiments 9427749, 10799501, 31871319, 20890305
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0016020 - membrane
GO:0031435 - mitogen-activated protein kinase kinase kinase binding
GO:0043525 - positive regulation of neuron apoptotic process
and 1 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 191
Hs

1 847
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024