HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: INF2 (Q27J81)
Inverted formin-2 (HBEBP2-binding protein C)
Gene: INF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Drf_FH3~Ras, Drf_GBD~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 1249
+	Hs
		925315 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		INF2_HUMAN (1-1249): 0: 873: 100.00
+	Hs
		564704 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		DIAP3_HUMAN (10-1092): 0: 666: 21.22
+	Hs
		1330940 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		DIAP3_HUMAN (10-1092): 0: 666: 21.22
+	Hs
		925658 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		DIAP3_HUMAN (10-1092): 0: 666: 21.22
+	Hs
		243091 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		DIAP2_HUMAN (10-1018): 0: 642: 21.82
+	Hs
		243112 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		DIAP2_HUMAN (10-1018): 0: 642: 21.82
+	Hs
		243100 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		DIAP2_HUMAN (10-1018): 0: 642: 21.82
+	Hs
		243096 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		DIAP2_HUMAN (10-1018): 0: 642: 21.82
+	Hs
		314890 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		FMNL1_HUMAN (40-1009): 1.21e-173: 545: 19.70
+	Hs
		314858 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		FMNL1_HUMAN (40-1009): 1.21e-173: 545: 19.70
+	Hs
		925531 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		FMNL2_HUMAN (10-1000): 6.58e-174: 545: 19.01
+	Hs
		314853 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		FMNL1_HUMAN (40-1009): 1.21e-173: 545: 19.70
+	Dd
		710114 RAC1A_DICDI (1-191): 6.92e-83: 245: 65.46		FORH_DICDI (50-1021): 2.46e-164: 520: 19.31
+	Hs
		925768 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		FHOD1_HUMAN (8-1069): 2.59e-160: 511: 14.30
+	Hs
		564754 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		DAAM1_HUMAN (507-1016): 1.8e-110: 374: 23.54
+	Hs
		1331005 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		DAAM1_HUMAN (507-1016): 1.8e-110: 374: 23.54
+	Hs
		925759 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		DAAM1_HUMAN (507-1016): 1.8e-110: 374: 23.54
+	Hs
		237586 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		DIAP1_HUMAN (10-532): 2.88e-73: 269: 21.30
+	Hs
		237577 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		DIAP1_HUMAN (10-532): 2.88e-73: 269: 21.30
+	Hs
		925673 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		FMN2_HUMAN (495-827): 8.34e-11: 68.9: 25.71