HitPredict

Interactor 1: ARP2 (P61160)
Actin-related protein 2 (Actin-like protein 2)
Gene: ACTR2

Interactor 2: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0015629 - actin cytoskeleton GO:0030478 - actin cap
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 394 Hs			1 793
+	Hs
		896944 ARP2_HUMAN (1-394): 0: 815: 100.00		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		724743 ARP2_HUMAN (1-394): 0: 815: 100.00		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		148602 ARP2_HUMAN (1-394): 0: 815: 100.00		CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87
+	Hs
		896980 ARP2_HUMAN (1-394): 0: 815: 100.00		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38
+	Hs
		891710 ACTB_HUMAN (1-388): 0: 574: 46.65		CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00
+	Hs
		929831 ACTG_HUMAN (3-388): 0: 573: 46.37		CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00
+	Hs
		891935 ACTB_HUMAN (1-388): 0: 574: 46.65		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Hs
		929952 ACTG_HUMAN (3-388): 0: 573: 46.37		MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98
+	Rn
		892236 ACTB_RAT (1-388): 0: 574: 46.65		MYH10_RAT (55-785): 3.7e-26: 117: 10.67
+	Mm
		892205 ACTB_MOUSE (1-388): 0: 574: 46.65		MYH9_MOUSE (2-638): 2.4e-23: 108: 10.87
+	Hs
		724738 ACTB_HUMAN (1-388): 0: 574: 46.65		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Rn
		892228 ACTB_RAT (1-388): 0: 574: 46.65		MYH9_RAT (2-603): 1.07e-21: 103: 10.66
+	Hs
		724762 ACTG_HUMAN (3-388): 0: 573: 46.37		MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87
+	Hs
		929869 ACTG_HUMAN (3-388): 0: 573: 46.37		PLEC_HUMAN (5-781): 2.36e-17: 89.5: 9.94
+	Rn
		92841 ACTB_RAT (1-388): 0: 574: 46.65		CTRO_RAT (81-718): 1.96e-16: 86.4: 9.75
+	Hs
		891686 ACTB_HUMAN (1-388): 0: 574: 46.65		MAP1A_HUMAN (212-642): 6.08e-13: 75: 18.04
+	Dm
		116373 ACT1_DROME (1-388): 0: 575: 45.88		M9PI41_DROME (26-625): 3.38e-10: 65.9: 12.21
+	Dm
		116372 ACT2_DROME (1-388): 0: 574: 45.62		M9PI41_DROME (26-625): 3.38e-10: 65.9: 12.21
+	Hs
		930015 ACTG_HUMAN (3-388): 0: 573: 46.37		MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38
+	Dm
		54871 ACT6_DROME (1-388): 0: 571: 46.13		A1ZA72_DROME (138-632): 5.06e-09: 62.2: 17.72