HitPredict

Interactor 1: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Interactor 2: ANTR1 (Q9H6X2)
Anthrax toxin receptor 1 (Tumor endothelial marker 8)
Gene: ANTXR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030036 - actin cytoskeleton organization GO:0034446 - substrate adhesion-dependent cell spreading
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 564
+	Hs
		925617 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		ANTR1_HUMAN (1-505): 0: 625: 100.00
+	Hs
		436510 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		ANTR1_HUMAN (1-505): 0: 625: 100.00
+	Hs
		951342 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		ANTR1_HUMAN (1-505): 0: 625: 100.00
+	Hs
		894435 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		ANTR1_HUMAN (1-505): 0: 625: 100.00
+	Hs
		545620 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		ANTR1_HUMAN (1-505): 0: 625: 100.00
+	Hs
		892598 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		ANTR1_HUMAN (1-505): 0: 625: 100.00
+	Hs
		915978 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		ANTR1_HUMAN (1-505): 0: 625: 100.00
+	Dr
		60120 RHOAB_DANRE (1-193): 9.16e-80: 237: 95.86		A4QP34_DANRE (20-489): 0: 535: 53.49
+	Hs
		885492 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		ANTR2_HUMAN (4-478): 0: 535: 55.46
+	Hs
		880209 RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00		ITA1_HUMAN (34-326): 1.84e-62: 224: 14.83
+	Hs
		880211 RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22		ITA1_HUMAN (34-326): 1.84e-62: 224: 14.83
+	Hs
		436228 RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71		ITA1_HUMAN (34-326): 1.84e-62: 224: 14.83
+	Hs
		880212 RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40		ITA1_HUMAN (34-326): 1.84e-62: 224: 14.83
+	Hs
		880208 CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33		ITA1_HUMAN (34-326): 1.84e-62: 224: 14.83
+	Hs
		545290 RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61		ITA1_HUMAN (34-326): 1.84e-62: 224: 14.83
+	Hs
		880207 RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54		ITA1_HUMAN (34-326): 1.84e-62: 224: 14.83
+	Hs
		880210 RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94		ITA1_HUMAN (34-326): 1.84e-62: 224: 14.83
+	Hs
		120368 RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98		ITA1_HUMAN (34-326): 1.84e-62: 224: 14.83