HitPredict

Interactor 1: RND3 (P61587)
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)
Gene: RND3

Interactor 2: PEAK1 (Q9H792)
Inactive tyrosine-protein kinase PEAK1 (Pseudopodium-enriched atypical kinase 1) (Sugen kinase 269) (Tyrosine-protein kinase SgK269)
Gene: PEAK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 244 Hs			1 1746
+	Hs
		852622 RND2_HUMAN (20-244): 3.9e-103: 300: 64.00		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		436511 RHOC_HUMAN (22-213): 2.02e-92: 271: 49.48		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		1269226 RND1_HUMAN (1-244): 1.22e-90: 268: 58.20		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		915979 RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		894437 CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		925619 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		545621 RAC2_HUMAN (24-211): 1.42e-76: 231: 39.89		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		900910 RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		892599 RAC3_HUMAN (24-199): 1.42e-75: 229: 43.75		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		951343 RHOG_HUMAN (23-208): 1.85e-74: 226: 42.47		PEAK1_HUMAN (1-1746): 0: 2185: 100.00
+	Hs
		436148 RHOC_HUMAN (22-213): 2.02e-92: 271: 49.48		KAPCA_HUMAN (1345-1709): 1.06e-90: 301: 18.30
+	Hs
		568605 CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00		KAPCA_HUMAN (1345-1709): 1.06e-90: 301: 18.30
+	Hs
		681775 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		AKT1_HUMAN (1362-1695): 4.43e-91: 307: 15.07
+	Hs
		568619 RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32		KAPCA_HUMAN (1345-1709): 1.06e-90: 301: 18.30
+	Hs
		568611 RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27		KAPCA_HUMAN (1345-1709): 1.06e-90: 301: 18.30
+	Hs
		1315495 RAB1B_HUMAN (16-242): 1.54e-76: 231: 21.49		PINK1_HUMAN (1357-1669): 2.87e-73: 258: 23.64
+	Hs
		900861 RHOA_HUMAN (25-207): 1.21e-76: 231: 50.27		PINK1_HUMAN (1357-1669): 2.87e-73: 258: 23.64
+	Hs
		616691 CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00		KS6B1_HUMAN (1453-1683): 8.42e-45: 173: 16.17
+	Ce
		136800 RHO1_CAEEL (22-200): 2.46e-93: 274: 50.28		UNC89_CAEEL (530-1704): 6.06e-21: 103: 12.80
+	Ce
		136793 RAC1_CAEEL (24-208): 1.83e-77: 233: 43.78		UNC89_CAEEL (530-1704): 6.06e-21: 103: 12.80