HitPredict

Interactor 1: SUMO2 (P61956)
Small ubiquitin-related modifier 2 (SUMO-2) (HSMT3) (SMT3 homolog 2) (SUMO-3) (Sentrin-2) (Ubiquitin-like protein SMT3B) (Smt3B)
Gene: SUMO2

Interactor 2: TOPRS (Q9NS56)
E3 ubiquitin-protein ligase Topors (EC 2.3.2.27) (RING-type E3 ubiquitin transferase Topors) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3)
Gene: TOPORS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	16524884
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016605 - PML body GO:0016925 - protein sumoylation
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 95 Hs			1 1045
+	Hs
		928207 SUMO1_HUMAN (1-93): 7.76e-35: 116: 45.36		TOPRS_HUMAN (1-1045): 0: 731: 100.00
+	Hs
		902632 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		NIPBL_HUMAN (362-1016): 7.16e-73: 267: 13.73
+	Hs
		902731 SUMO2_HUMAN (1-95): 3.56e-44: 139: 100.00		SCAFB_HUMAN (465-951): 2.34e-12: 73.5: 13.03