HitPredict

Interactor 1: PP1B (P62141)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: Ppp1cb

Interactor 2: NEB2 (Q6R891)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: Ppp1r9b

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30562941
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Metallophos~PDZ, Metallophos~PDZ_5, PDZ~STPPase_N, PDZ_5~STPPase_N
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 327 Mm			1 817
+	Rn
		192520 PP1B_RAT (1-327): 0: 597: 100.00		NEB2_RAT (1-817): 2.42e-118: 379: 98.90
+	Hs
		906570 PP1B_HUMAN (1-327): 0: 597: 100.00		NEB2_HUMAN (1-817): 5.5e-113: 365: 95.84
+	Rn
		192519 PP1A_RAT (1-326): 0: 576: 88.79		NEB2_RAT (1-817): 2.42e-118: 379: 98.90
+	Mm
		906288 PP1A_MOUSE (1-326): 0: 576: 88.49		NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00
+	Rn
		192521 PP1G_RAT (1-327): 0: 569: 86.89		NEB2_RAT (1-817): 2.42e-118: 379: 98.90
+	Mm
		926545 PP1G_MOUSE (1-327): 0: 569: 86.89		NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00
+	Hs
		906098 PP1A_HUMAN (1-326): 0: 576: 88.79		NEB2_HUMAN (1-817): 5.5e-113: 365: 95.84
+	Hs
		906629 PP1B_HUMAN (1-327): 0: 597: 100.00		NEB1_HUMAN (1-817): 1.2e-100: 338: 46.50
+	Hs
		737997 PP1G_HUMAN (1-327): 0: 569: 86.89		NEB2_HUMAN (1-817): 5.5e-113: 365: 95.84
+	Hs
		906197 PP1A_HUMAN (1-326): 0: 576: 88.79		NEB1_HUMAN (1-817): 1.2e-100: 338: 46.50
+	Rn
		193533 PP1B_RAT (1-327): 0: 597: 100.00		NEB1_RAT (1-817): 1.17e-92: 316: 45.86
+	Hs
		738120 PP1G_HUMAN (1-327): 0: 569: 86.89		NEB1_HUMAN (1-817): 1.2e-100: 338: 46.50
+	Rn
		193534 PP1G_RAT (1-327): 0: 569: 86.89		NEB1_RAT (1-817): 1.17e-92: 316: 45.86
+	Hs
		906059 PP1A_HUMAN (1-326): 0: 576: 88.79		DLG3_HUMAN (269-734): 1.64e-40: 162: 16.36
+	Mm
		906652 PP1B_MOUSE (1-327): 0: 597: 100.00		DLG4_MOUSE (381-806): 1.83e-31: 133: 11.04
+	Mm
		926531 PP1G_MOUSE (1-327): 0: 569: 86.89		DLG3_MOUSE (224-734): 1.59e-39: 159: 16.23
+	Hs
		906031 PP1A_HUMAN (1-326): 0: 576: 88.79		LNX1_HUMAN (224-773): 4.36e-33: 138: 11.92
+	Mm
		906274 PP1A_MOUSE (1-326): 0: 576: 88.49		DLG4_MOUSE (381-806): 1.83e-31: 133: 11.04
+	Hs
		737775 PP1G_HUMAN (1-327): 0: 569: 86.89		DLG1_HUMAN (80-763): 3.75e-33: 139: 11.22
+	Hs
		905921 PP1A_HUMAN (1-326): 0: 576: 88.79		DLG2_HUMAN (413-817): 2.76e-25: 114: 14.35