HitPredict

Interactor 1: AFF1 (P51825)
AF4/FMR2 family member 1 (ALL1-fused gene from chromosome 4 protein) (Protein AF-4) (Protein FEL) (Proto-oncogene AF4)
Gene: AFF1

Interactor 2: DYR1A (Q13627)
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)
Gene: DYRK1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31024071
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AF-4~Pkinase
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1210 Hs			1 763
+	Hs
		1116183 PCLO_HUMAN (6-981): 6.88e-22: 105: 9.63		DYR1A_HUMAN (1-763): 0: 620: 100.00
+	Hs
		1115936 CIC_HUMAN (222-1000): 3.42e-13: 77: 8.22		DYR1A_HUMAN (1-763): 0: 620: 100.00
+	Hs
		1116007 TARA_HUMAN (273-985): 1.73e-11: 71.2: 9.94		DYR1A_HUMAN (1-763): 0: 620: 100.00
+	Hs
		161464 KMT2D_HUMAN (23-1021): 4.87e-11: 69.7: 10.24		DYR1A_HUMAN (1-763): 0: 620: 100.00
+	Hs
		443548 AFF4_HUMAN (10-1208): 4.37e-90: 318: 33.78		CDK1_HUMAN (156-482): 5.61e-122: 369: 26.57
+	Hs
		1115838 THOC2_HUMAN (560-916): 5.65e-09: 62.8: 15.61		DYR1A_HUMAN (1-763): 0: 620: 100.00
+	Hs
		1401467 CIC_HUMAN (222-1000): 3.42e-13: 77: 8.22		DYR1B_HUMAN (57-600): 1.52e-139: 427: 68.13
+	Hs
		1361881 TITIN_HUMAN (98-995): 5.6e-15: 82.8: 9.39		DYRK2_HUMAN (46-549): 2.32e-120: 376: 33.53
+	Hs
		1366128 TARA_HUMAN (273-985): 1.73e-11: 71.2: 9.94		DYRK2_HUMAN (46-549): 2.32e-120: 376: 33.53
+	Hs
		443483 CIC_HUMAN (222-1000): 3.42e-13: 77: 8.22		CDK1_HUMAN (156-482): 5.61e-122: 369: 26.57
+	Hs
		667952 TITIN_HUMAN (98-995): 5.6e-15: 82.8: 9.39		CDK2_HUMAN (156-421): 2.08e-118: 360: 26.76
+	Hs
		161418 KMT2D_HUMAN (23-1021): 4.87e-11: 69.7: 10.24		AKT1_HUMAN (38-466): 1.32e-119: 369: 19.42