HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: ABI2 (Q9NYB9)
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Gene: ABI2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001764 - neuron migration GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding and 1 others more... GO:0035591 - signaling adaptor activity
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 513
+	Hs
		909798 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ABI1_HUMAN (1-513): 3.84e-97: 304: 61.00
+	Hs
		297821 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		K0754_HUMAN (111-451): 1.58e-28: 122: 16.09
+	Sp
		788710 RAD24_SCHPO (2-255): 7.25e-135: 382: 70.77		CDC15_SCHPO (131-508): 1.09e-34: 141: 17.57
+	Hs
		909551 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ARHG7_HUMAN (451-508): 2.16e-18: 90.8: 41.38
+	Mm
		910262 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		DBNL_MOUSE (293-508): 1.64e-17: 87: 22.07
+	Mm
		910242 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		SRBS2_MOUSE (371-509): 7.72e-17: 85.9: 21.53
+	Hs
		298967 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SRBS2_HUMAN (373-509): 1.11e-16: 85.5: 19.87
+	Hs
		299007 V9HW98_HUMAN (1-255): 4.87e-154: 430: 100.00		SRBS2_HUMAN (373-509): 1.11e-16: 85.5: 19.87
+	Hs
		909427 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93
+	Hs
		909849 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SH3R3_HUMAN (370-508): 3.57e-10: 64.7: 20.14