HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: JAM3 (Q9BX67)
Junctional adhesion molecule C (JAM-C) (JAM-2) (Junctional adhesion molecule 3) (JAM-3) [Cleaved into: Soluble form of JAM-C (sJAM-C)]
Gene: JAM3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0001525 - angiogenesis GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 310
+	Hs
		916104 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		JAM1_HUMAN (14-310): 5.99e-58: 190: 31.21
+	Hs
		925182 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		925776 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		ROBO1_HUMAN (22-239): 7.6e-37: 141: 19.91
+	Hs
		900368 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		915596 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		545313 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		901110 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		ROBO1_HUMAN (22-239): 7.6e-37: 141: 19.91
+	Hs
		916112 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ROBO1_HUMAN (22-239): 7.6e-37: 141: 19.91
+	Hs
		894276 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		PXDN_HUMAN (27-239): 9.9e-39: 147: 20.19
+	Hs
		436250 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		940394 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		436602 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		ROBO1_HUMAN (22-239): 7.6e-37: 141: 19.91
+	Hs
		892311 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		893890 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		894644 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		ROBO1_HUMAN (22-239): 7.6e-37: 141: 19.91
+	Hs
		564473 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		CXAR_HUMAN (15-297): 3.8e-39: 143: 19.33
+	Hs
		530163 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		NCAM1_HUMAN (18-306): 7.35e-25: 106: 12.91
+	Hs
		915989 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ROBO2_HUMAN (134-310): 1.67e-19: 91.1: 15.71
+	Hs
		915881 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		NEO1_HUMAN (26-245): 4.21e-16: 81.1: 9.69
+	Hs
		564637 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		NEO1_HUMAN (26-245): 4.21e-16: 81.1: 9.69