HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: UACA (Q9BZF9)
Uveal autoantigen with coiled-coil domains and ankyrin repeats
Gene: UACA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 1416
+	Hs
		925723 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		KDIS_HUMAN (1-203): 7.97e-44: 177: 25.24
+	Hs
		901042 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		KDIS_HUMAN (1-203): 7.97e-44: 177: 25.24
+	Hs
		916068 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		KDIS_HUMAN (1-203): 7.97e-44: 177: 25.24
+	Hs
		545696 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		KDIS_HUMAN (1-203): 7.97e-44: 177: 25.24
+	Hs
		951304 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		UACA_HUMAN (3-1323): 6.02e-45: 180: 14.97
+	Hs
		925238 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		ANK3_HUMAN (75-382): 1.44e-41: 170: 18.40
+	Hs
		436568 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		KDIS_HUMAN (1-203): 7.97e-44: 177: 25.24
+	Hs
		951454 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		KDIS_HUMAN (1-203): 7.97e-44: 177: 25.24
+	Hs
		900423 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		ANK3_HUMAN (75-382): 1.44e-41: 170: 18.40
+	Hs
		915638 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ANK3_HUMAN (75-382): 1.44e-41: 170: 18.40
+	Hs
		950953 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		ANK3_HUMAN (75-382): 1.44e-41: 170: 18.40
+	Hs
		893947 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		ANK3_HUMAN (75-382): 1.44e-41: 170: 18.40
+	Hs
		883465 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		RIPK4_HUMAN (93-382): 1.35e-34: 145: 20.62
+	Hs
		925681 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RAI14_HUMAN (987-1410): 1.86e-29: 129: 32.55
+	Hs
		900992 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		RAI14_HUMAN (987-1410): 1.86e-29: 129: 32.55
+	Hs
		916033 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		RAI14_HUMAN (987-1410): 1.86e-29: 129: 32.55
+	Hs
		951418 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		RAI14_HUMAN (987-1410): 1.86e-29: 129: 32.55
+	Hs
		894528 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		RAI14_HUMAN (987-1410): 1.86e-29: 129: 32.55
+	Hs
		545454 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		POTEE_HUMAN (27-486): 5e-20: 99.2: 14.48
+	Hs
		925423 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		HACE1_HUMAN (102-374): 1.34e-09: 65.1: 25.52