HitPredict

Interactor 1: C9JXZ5 (C9JXZ5)
Vesicle associated membrane protein 8
Gene: VAMP8

Interactor 2: STX8 (Q9UNK0)
Syntaxin-8
Gene: STX8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	SNARE~Synaptobrevin
Common GO terms	GO:0012505 - endomembrane system
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 74 Hs			1 236
+	Dm
		1263473 Q7JYX5_DROME (1-74): 3.6e-24: 91.5: 36.49		Q9VV76_DROME (4-223): 7.24e-43: 146: 24.32
+	Dm
		614962 SYB_DROME (1-69): 8.2e-25: 91.5: 30.44		Q9VV76_DROME (4-223): 7.24e-43: 146: 24.32
+	Rn
		1224612 VAMP1_RAT (1-59): 1.98e-21: 81.9: 33.90		STX6_RAT (3-222): 3.22e-46: 155: 17.65
+	Hs
		908065 VAMP7_HUMAN (1-74): 4.93e-19: 78.4: 39.19		STX8_HUMAN (1-218): 7.58e-47: 156: 100.00
+	Dm
		1487159 NSYB_DROME (1-65): 1.68e-21: 83.8: 32.31		Q9VV76_DROME (4-223): 7.24e-43: 146: 24.32
+	Hs
		225968 VAMP7_HUMAN (1-74): 4.93e-19: 78.4: 39.19		STX6_HUMAN (3-221): 2.27e-43: 148: 17.30
+	At
		1456080 VA721_ARATH (1-73): 2.76e-23: 89.2: 38.36		SNP33_ARATH (11-210): 1.8e-38: 137: 15.69
+	At
		866335 VA722_ARATH (1-73): 1.97e-22: 87.2: 36.99		SNP33_ARATH (11-210): 1.8e-38: 137: 15.69
+	Sc
		751601 SNC2_YEAST (1-55): 1.59e-20: 79.5: 29.09		TLG1_YEAST (2-220): 3.97e-32: 118: 15.07
+	Sc
		1042346 NYV1_YEAST (1-69): 4.98e-18: 76.5: 26.09		TLG1_YEAST (2-220): 3.97e-32: 118: 15.07
+	Hs
		343318 VAMP1_HUMAN (2-59): 6.09e-21: 80.7: 32.76		SNP29_HUMAN (10-207): 2.96e-28: 109: 20.50
+	Hs
		343334 VAMP7_HUMAN (1-74): 4.93e-19: 78.4: 39.19		SNP29_HUMAN (10-207): 2.96e-28: 109: 20.50
+	Sc
		748209 SNC2_YEAST (1-55): 1.59e-20: 79.5: 29.09		VAM7_YEAST (46-211): 1.29e-25: 103: 21.56
+	Dm
		614909 SYB_DROME (1-69): 8.2e-25: 91.5: 30.44		Q7JRF1_DROME (3-138): 1.11e-20: 90.3: 14.29
+	Sc
		652916 SNC2_YEAST (1-55): 1.59e-20: 79.5: 29.09		BET1_YEAST (93-235): 4.91e-27: 102: 18.06
+	Sc
		748249 NYV1_YEAST (1-69): 4.98e-18: 76.5: 26.09		VAM7_YEAST (46-211): 1.29e-25: 103: 21.56
+	Sc
		652943 NYV1_YEAST (1-69): 4.98e-18: 76.5: 26.09		BET1_YEAST (93-235): 4.91e-27: 102: 18.06
+	Hs
		179853 VAMP7_HUMAN (1-74): 4.93e-19: 78.4: 39.19		BET1_HUMAN (149-234): 6.34e-25: 96.8: 18.61
+	Dm
		1263475 Q7JYX5_DROME (1-74): 3.6e-24: 91.5: 36.49		Q9VVX6_DROME (161-234): 4.71e-13: 65.7: 20.00
+	Dm
		614963 SYB_DROME (1-69): 8.2e-25: 91.5: 30.44		Q9VVX6_DROME (161-234): 4.71e-13: 65.7: 20.00