HitPredict

Interactor 1: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Interactor 2: ANR44 (Q8N8A2)
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (PP6-ARS-B) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-B) (Ankyrin repeat domain-containing protein 44)
Gene: ANKRD44

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.80	0.705

Property	Details
Experiments	29764989, 19596235
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank~Pkinase, Ank_2~Pkinase, Ank_4~Pkinase
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 603 Hs			1 993
+	Hs
		919920 PLK1_HUMAN (1-603): 0: 619: 100.00		ANK3_HUMAN (539-993): 1.53e-104: 362: 25.77
+	Hs
		177189 PLK1_HUMAN (1-603): 0: 619: 100.00		ANR28_HUMAN (740-993): 5.26e-48: 188: 29.41
+	Hs
		274124 PLK1_HUMAN (1-603): 0: 619: 100.00		ANR17_HUMAN (820-992): 1.52e-38: 158: 25.99
+	Hs
		920119 PLK1_HUMAN (1-603): 0: 619: 100.00		ANR52_HUMAN (804-992): 2.97e-36: 150: 30.16
+	Hs
		920098 PLK1_HUMAN (1-603): 0: 619: 100.00		ANKH1_HUMAN (828-992): 2.7e-34: 145: 24.85
+	Hs
		177318 PLK2_HUMAN (38-587): 1.05e-163: 485: 36.53		ANR28_HUMAN (740-993): 5.26e-48: 188: 29.41
+	Hs
		1331015 PLK2_HUMAN (38-587): 1.05e-163: 485: 36.53		ANR44_HUMAN (739-993): 1.45e-46: 183: 28.91