Interactor 1: PLK1 (P53350)
Serine/threonine-protein kinase PLK1 (EC 2.7.11.21) (Polo-like kinase 1) (PLK-1) (Serine/threonine-protein kinase 13) (STPK13)
Gene: PLK1

Interactor 2: CDC23 (Q9UJX2)
Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8)
Gene: CDC23

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 29764989
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000278 - mitotic cell cycle
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0007091 - metaphase/anaphase transition of mitotic cell cycle
GO:0007346 - regulation of mitotic cell cycle
and 2 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 603
Hs

1 597
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Hs
+ Sp
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+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025