HitPredict

Interactor 1: GBB1 (P62871)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Interactor 2: GNAI1 (P63097)
Guanine nucleotide-binding protein G(i) subunit alpha-1 (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI1

Species: Bos taurus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	20018744
Identification Methods	nuclear magnetic resonance
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	G-alpha~WD40
Common GO terms	GO:0005737 - cytoplasm GO:0005834 - heterotrimeric G-protein complex GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 340 Bt			1 354
+	Hs
		921512 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		GNAI1_HUMAN (1-354): 0: 512: 100.00
+	Hs
		920929 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		GNAI1_HUMAN (1-354): 0: 512: 100.00
+	Hs
		926713 GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88		GNAI1_HUMAN (1-354): 0: 512: 100.00
+	Hs
		444706 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		GNAI3_HUMAN (1-354): 1.51e-179: 503: 93.79
+	Hs
		444705 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		GNAI3_HUMAN (1-354): 1.51e-179: 503: 93.79
+	Hs
		444791 GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88		GNAI3_HUMAN (1-354): 1.51e-179: 503: 93.79
+	Hs
		391374 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		GNAI2_HUMAN (1-354): 3.51e-178: 499: 87.89
+	Hs
		391373 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		GNAI2_HUMAN (1-354): 3.51e-178: 499: 87.89
+	Hs
		391465 GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88		GNAI2_HUMAN (1-354): 3.51e-178: 499: 87.89
+	Hs
		451000 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		GNAO_HUMAN (1-354): 4.45e-175: 491: 72.11
+	Ce
		567431 GBB1_CAEEL (1-340): 7.67e-107: 317: 85.88		GNAO_CAEEL (1-354): 2.29e-171: 482: 69.86
+	Mm
		579642 GBB1_MOUSE (1-340): 7.02e-105: 312: 100.00		GNAO_MOUSE (1-354): 1.59e-172: 485: 71.83
+	Bt
		387977 GBB1_BOVIN (1-340): 7.02e-105: 312: 100.00		GNAT1_BOVIN (1-354): 8.16e-169: 475: 67.80
+	Hs
		837600 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		GNAQ_HUMAN (1-353): 3.49e-167: 472: 52.26
+	Hs
		670451 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		GNA11_HUMAN (1-353): 1.33e-162: 460: 51.13
+	Hs
		921564 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		GNA13_HUMAN (2-353): 1.72e-155: 443: 39.17
+	Hs
		920966 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		GNA13_HUMAN (2-353): 1.72e-155: 443: 39.17
+	Hs
		921511 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		GNAS2_HUMAN (1-354): 3.5e-143: 412: 38.23
+	Hs
		920928 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		GNAS2_HUMAN (1-354): 3.5e-143: 412: 38.23
+	Hs
		926641 GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88		GNAS2_HUMAN (1-354): 3.5e-143: 412: 38.23