HitPredict

Interactor 1: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Interactor 2: PKHG2 (Q9H7P9)
Pleckstrin homology domain-containing family G member 2 (PH domain-containing family G member 2)
Gene: PLEKHG2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	1.00	0.806

Property	Details
Experiments	27765816, 18045877
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	PH~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 340 Hs			1 1386
+	Hs
		921674 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		ARHG2_HUMAN (5-827): 8.44e-102: 350: 14.55
+	Hs
		166481 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		MCF2L_HUMAN (16-617): 2.15e-92: 326: 21.80
+	Hs
		500933 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		MCF2_HUMAN (22-498): 1.8e-92: 322: 20.92
+	Hs
		921728 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		ECT2_HUMAN (8-497): 1.14e-79: 285: 21.79
+	Hs
		1333738 GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88		ECT2_HUMAN (8-497): 1.14e-79: 285: 21.79
+	Hs
		921052 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		ECT2_HUMAN (8-497): 1.14e-79: 285: 21.79
+	Hs
		560889 GBB3_HUMAN (1-340): 1.83e-104: 311: 83.24		ECT2_HUMAN (8-497): 1.14e-79: 285: 21.79
+	Hs
		224710 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		KALRN_HUMAN (3-599): 1.18e-75: 280: 17.52
+	Hs
		903416 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		ARHG2_HUMAN (5-827): 8.44e-102: 350: 14.55
+	Hs
		1288311 SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30		ECT2_HUMAN (8-497): 1.14e-79: 285: 21.79
+	Hs
		903526 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		ECT2_HUMAN (8-497): 1.14e-79: 285: 21.79
+	Hs
		1254029 NLE1_HUMAN (3-124): 6.68e-32: 126: 25.41		PREX1_HUMAN (40-452): 3.91e-85: 309: 24.12