HitPredict

Interactor 1: GBB1 (P62874)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: Gnb1

Interactor 2: A16L1 (Q8C0J2)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: Atg16l1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30196744
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005737 - cytoplasm GO:0051020 - GTPase binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 340 Mm			1 607
+	Mm
		921801 GBB2_MOUSE (1-340): 1e-105: 314: 90.29		A16L1_MOUSE (1-607): 1.3e-159: 472: 100.00
+	Hs
		921751 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		NLE1_HUMAN (173-474): 1.25e-54: 194: 16.19
+	Hs
		920927 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		GBB1_HUMAN (165-516): 4.59e-45: 164: 17.18
+	Hs
		921054 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		GBB4_HUMAN (165-516): 1.18e-45: 166: 16.34
+	Hs
		560870 GBB3_HUMAN (1-340): 1.83e-104: 311: 83.24		GBB1_HUMAN (165-516): 4.59e-45: 164: 17.18
+	Hs
		921608 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		A16L1_HUMAN (441-605): 1.08e-24: 110: 16.36
+	Hs
		920988 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		A16L1_HUMAN (441-605): 1.08e-24: 110: 16.36
+	Dm
		1358845 WDS_DROME (3-215): 1.22e-57: 192: 19.55		WDS_DROME (193-478): 2.99e-63: 214: 18.03
+	Sc
		630844 NLE1_YEAST (2-297): 8.98e-80: 253: 18.55		NLE1_YEAST (446-606): 1.83e-38: 150: 14.45
+	Hs
		903551 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		NLE1_HUMAN (173-474): 1.25e-54: 194: 16.19
+	Hs
		792949 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		LIS1_HUMAN (44-438): 1.05e-51: 184: 14.87
+	Hs
		903349 WDR5B_HUMAN (71-340): 2.74e-83: 257: 25.18		WDR5_HUMAN (194-352): 8.47e-14: 74.7: 10.00
+	Hs
		1016312 SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30		TBL3_HUMAN (292-487): 1.61e-17: 88.6: 27.32
+	Hs
		903174 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		TBL3_HUMAN (292-487): 1.61e-17: 88.6: 27.32
+	Hs
		903428 SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30		WDR5_HUMAN (194-352): 8.47e-14: 74.7: 10.00
+	Hs
		903077 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		WDR5_HUMAN (194-352): 8.47e-14: 74.7: 10.00